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  1. Knockout Transporter Cell Lines to Assess Substrate Potential Towards Efflux Transporters

    P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and multidrug resistance transporter 2 (MRP2) are efflux transporters involved in the...

    Donna A. Volpe in The AAPS Journal
    Article Open access 10 July 2024
  2. Establishment of a multi-line immunochromatography based on magnetic nanoparticles for simultaneous screening of multiple biomarkers

    Biomarkers screening is a benefit approach for early diagnosis of major diseases. In this study, magnetic nanoparticles (MNPs) have been utilized as...

    Liyue Shen, Tao Peng, ... **nhua Dai in Analytical and Bioanalytical Chemistry
    Article 10 July 2024
  3. Intramolecular [π4s + π4s] photocycloaddition of carbon- and nitrogen-bridged [32](1,4)naphthalenophanes

    [3 2 ](1,4)Naphthalenophanes, bearing carbon-bridge chains ( syn - and anti - NPs ) and nitrogen-bridge chains ( syn - and anti - ANPs ), were synthesized, and...

    Yukiko Oguma, Masanori Yamamoto, ... Hideki Okamoto in Photochemical & Photobiological Sciences
    Article Open access 10 July 2024
  4. Rapid analysis of untreated food samples by gel loading tip spray ionization mass spectrometry

    Rapid, efficient, versatile, easy-to-use, and non-expensive analytical approaches are globally demanded for food analysis. Many ambient ionization...

    Md. Matiur Rahman, Shuanglong Wang, ... Konstantin Chingin in Analytical and Bioanalytical Chemistry
    Article 10 July 2024
  5. Niclosamide modulates phenotypic switch and inflammatory responses in human pulmonary arterial smooth muscle cells

    Excessive proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) represent key steps of pulmonary vascular remodeling,...

    Yuwen Lu, **aogan Liang, ... Ni Zhu in Molecular and Cellular Biochemistry
    Article 09 July 2024
  6. Evaluating the Impact of an Organic Trace Mineral mix on the Redox Homeostasis, Immunity, and Performance of Sows and their Offspring

    The objective of the study was to evaluate the effects of trace mineral supplementation in sows during gestation and lactation on the performance and...

    Shao-Qing Wang, Zhe Peng, ... Zhang-Chao Deng in Biological Trace Element Research
    Article 09 July 2024
  7. KIAA1429 promotes the malignancy of oral squamous cell carcinoma by regulating CA9 m6A methylation

    KIAA1429 has been reported as a cancer regulator, but its role and mechanism in the progression of oral squamous cell carcinoma (OSCC) remain...

    Jia Tu, **ao Feng, ... Yan Guan in Cytotechnology
    Article 09 July 2024
  8. Delineation of the phenotypes and genotypes of PIK3CA-related overgrowth spectrum in East asians

    PIK3CA -related overgrowth spectrum (PROS) is an umbrella term to describe a diverse range of developmental disorders. Research to date has...

    Hongrui Chen, Bin Sun, ... **aoxi Lin in Molecular Genetics and Genomics
    Article 09 July 2024
  9. Phylogenetic Diversity Indices from an Affine and Projective Viewpoint

    Phylogenetic diversity indices are commonly used to rank the elements in a collection of species or populations for conservation purposes. The...

    V. Moulton, A. Spillner, K. Wicke in Bulletin of Mathematical Biology
    Article Open access 09 July 2024
  10. David J. Glass elected to the U.S. National Academy of Sciences

    Se-** Lee, Bruce Spiegelman, Kevin Campbell in Skeletal Muscle
    Article Open access 09 July 2024
  11. An updated and comprehensive review of traditional uses, phytochemistry, and pharmacological progress on the Hypecoum genus

    The Hypecoum genus belongs to the family Papaveraceae, consists of roughly 16 accepted species, and is extensively distributed from the Mediterranean...

    Hai-Lian Yuan, Li Zhang, ... **ao-Dong Luo in Phytochemistry Reviews
    Article 09 July 2024
  12. A Mouse Model of Sporadic Alzheimer’s Disease with Elements of Major Depression

    After olfactory bulbectomy, animals are often used as a model of major depression or sporadic Alzheimer’s disease and, hence, the status of this...

    N. V. Bobkova, L. N. Chuvakova, ... M. B. Evgen’ev in Molecular Neurobiology
    Article 09 July 2024
  13. Phylloquinone improves endothelial function, inhibits cellular senescence, and vascular inflammation

    Phylloquinon (PK) and menaquinones (MK) are both naturally occurring compounds belonging to vitamin K group. Present study aimed to comprehensively...

    Anna Kieronska-Rudek, Agnieszka Kij, ... Stefan Chlopicki in GeroScience
    Article Open access 09 July 2024
  14. Small Non-Coding sRNA53 Modulates the Quorum Sensing System to Enhance Drug Resistance in Escherichia coli Exposed to Heavy Ion and X-ray Irradiation

    Abstract

    Small non-coding RNAs (sRNAs, also called sncRNAs) known as gene expression regulatory factors are capable of modulating mRNA functions...

    S. J. Zhao, X. Y. Pang, ... X. Li in Molecular Biology
    Article 09 July 2024
  15. Dynamic Transcriptional Programs During Single NK Cell Killing: Connecting Form to Function in Cellular Immunotherapy

    Introduction

    Natural killer (NK) cell-based therapies are a promising new method for treating indolent cancer, however engineering new therapies is...

    Joseph T. Decker, Matthew S. Hall, ... Lonnie D. Shea in Cellular and Molecular Bioengineering
    Article 09 July 2024
  16. Design and Numerical Analysis of a Fractal Tree Shaped Graphene Based Metasurface Solar Absorber

    This study introduces a novel solar absorber design using a fractal tree-shaped graphene-based metasurface. The absorber structure consists of...

    Sandip Das, Riya Sen, Sunil Sharma in Plasmonics
    Article 09 July 2024
  17. Genomic Insights into the Landfill Microbial Community: Denitrifying Activity Supporting One-Carbon Utilization

    In spite of the developments in understanding of denitrifying methylotrophy in the recent years, challenges still exist in unravelling the overall...

    Bhagyashri J. Poddar, Anshuman A. Khardenavis in Applied Biochemistry and Biotechnology
    Article 09 July 2024
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