Search
Search Results
-
Mitochondrial DNA abundance in blood is associated with Alzheimer’s disease- and dementia-risk
The mitochondrial cascade hypothesis of Alzheimer’s disease (AD) has been portrayed through molecular, cellular, and animal studies; however large...
-
Cognitive asymmetry in rats in response to emergent vs. disappearing affordances
This study examines the effects of novel environmental changes on the behavior of rats in an experimental chamber. We hypothesized that newly...
-
-
Impact of physical activity on caloric and macronutrient intake in children and adolescents: a systematic review and meta-analysis of randomized controlled trials
BackgroundPhysical activity is widely promoted to maintain and improve health across all ages. Investigating how physical activity affects subsequent...
-
A nonoscillatory, millisecond-scale embedding of brain state provides insight into behavior
The most robust and reliable signatures of brain states are enriched in rhythms between 0.1 and 20 Hz. Here we address the possibility that the...
-
(Re)Emerging disease and conflict risk in Africa, 1997–2019
While the number of infectious zoonotic disease outbreaks has been rising, their impact on civil war and social conflict is poorly understood. This...
-
Unlocking opioid neuropeptide dynamics with genetically encoded biosensors
Neuropeptides are ubiquitous in the nervous system. Research into neuropeptides has been limited by a lack of experimental tools that allow for the...
-
Prevalence and correlates of common mental disorders among participants of the Uganda Genome Resource: Opportunities for psychiatric genetics research
Genetics research has potential to alleviate the burden of mental disorders in low- and middle-income-countries through identification of new...
-
PET imaging of neuroinflammation: any credible alternatives to TSPO yet?
Over the last decades, the role of neuroinflammation in neuropsychiatric conditions has attracted an exponentially growing interest. A key driver for...
-
Where do Harris’ Checkerspots Lay their Eggs and what are the Consequences?
Where a female lays her eggs has strong implications for the survival of her offspring, an impetus that takes on particular significance for species...
-
Evaluation of the Irrigation Water Quality of Beressa River, North West Ethiopia
Beressa River is facing a problem due to uncontrolled discharge of liquid wastes from domestics and industries. Therefore, the study was conducted to...
-
A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior
The single nucleotide polymorphism rs13166360, causing a substitution of valine (Val) 147 to leucine (Leu) in the adenylyl cyclase 2 (ADCY2), has...
-
Immune challenge reduces begging effort and modifies begging call structure in spotless starling nestlings
Symptoms of illness offer insights into an organism’s condition, altering social signals that affect others’ behavior. Nestling birds employ begging...
-
Application of GWAS summary data and drug-induced gene expression profiles of neural progenitor cells in psychiatric drug prioritization analysis
Common psychiatric disorders constitute one of the most substantial healthcare burdens worldwide. However, drug development in psychiatry remains...
-
Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number
Neuroligin-3 ( Nlgn3 ) is an autism-associated cell-adhesion molecule that interacts with neurexins and is robustly expressed in both neurons and...
-
Multimodal training protocols on unstable rather than stable surfaces better improve dynamic balance ability in older adults
BackgroundThere has been growing interest in using unstable devices in training protocols. This study aimed to assess the effectiveness of two...
-
Estrogen receptor beta signaling enhances extinction memory recall for heroin-conditioned cues in a sex- and region-specific manner
Return to use, or relapse, is a major challenge in the treatment of opioid use disorder (OUD). Relapse can be precipitated by several factors,...
-
Trauma, adversity, and biological aging: behavioral mechanisms relevant to treatment and theory
Although stress and adversity are largely universal experiences, people exposed to greater hardship are at increased risk for negative health...
-
Vitamin C Alleviates Neurobehavioral Deficits, IGF1 Expression, and Neuronal Damage Induced by Chronic Social Isolation Stress in the Hippocampus of Adult Male Rats
Social isolation stress (SIS) is associated with emotional and cognitive deficits. Here, we examined the impact of prolonged treatment with vitamin C...
-
Traditional Herbal Remedies Used in the Management of Urolithiasis by the Tribals of Purulia District, West Bengal, India
The tribal populations in Purulia district directly or indirectly rely on medicinal plants for their basic medical needs. Urolithiasis is the...
