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Advancing microarray fabrication: One-pot synthesis and high-resolution patterning of UV-crosslinkable perovskite quantum dots
The development of highly efficient, solution-processable, and environmentally stable perovskite quantum dots (PQDs) is crucial for their accurate...
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A randomised controlled trial of Standard Of Care versus RadioAblaTion in Early Stage HepatoCellular Carcinoma (SOCRATES HCC)
BackgroundTherapeutic options for early-stage hepatocellular carcinoma (HCC) in individual patients can be limited by tumor and location, liver...
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Mining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning
BackgroundThe advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack...
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Silencing of ultradian rhythms and metabolic depression during spontaneous daily torpor in Djungarian hamsters
Ultradian rhythms of metabolism, body temperature and activity are attenuated or disappear completely during torpor in Djungarian hamsters, for all...
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Nano-Se exhibits limited protective effect against heat stress induced poor breast muscle meat quality of broilers compared with other selenium sources
BackgroundAt present, heat stress (HS) has become a key factor that impairs broiler breeding industry, which causes growth restriction and poor meat...
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Effect of combined physical–cognitive training on the functional and cognitive capacity of older people with mild cognitive impairment: a randomized controlled trial
BackgroundThe increase in population aging highlights the growing prevalence of mild cognitive impairment, prompting the adoption of interventions...
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A longitudinal multi-centric cohort study assessing infant neurodevelopment delay among women with persistent postpartum depression in Nepal
BackgroundInfant neurodevelopment in the first years after birth is determined by multiple factors, including parental care and maternal mental...
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Global incidence and characteristics of spinal cord injury since 2000–2021: a systematic review and meta-analysis
BackgroundThis study employs systematic review and meta-analysis to explore the incidence and characteristics of spinal cord injury (SCI) between...
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Vaginal and rectal microbiome contribute to genital inflammation in chronic pelvic pain
BackgroundChronic pelvic pain (CPP) is a multifactorial syndrome that can substantially affect a patient’s quality of life. Endometriosis is one...
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Genetic therapies for cardiomyopathy: survey of attitudes of the patient community for the CureHeart project
Cardiomyopathies are a group of inherited heart muscle disorders. Expressivity is variable and while sometimes mild, complications can result in...
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Using a new analytic approach for genoty** and phenoty** chromosome 9p deletion syndrome
Using a new analytic method (“unique non-overlap** region” (UNOR) analysis), we characterized the genotypes and phenotypes of a large cohort of...
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Comparative immune profiling of pancreatic ductal adenocarcinoma progression among South African patients
BackgroundPancreatic Ductal Adenocarcinoma (PDAC) is an aggressive cancer characterized by an immunosuppressive microenvironment. Patients from...
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Ultrasound-based nomogram to predict the recurrence in papillary thyroid carcinoma using machine learning
Background and aimsThe recurrence of papillary thyroid carcinoma (PTC) is not unusual and associated with risk of death. This study is aimed to...
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Effects of altering the ratio of C16:0 and cis-9 C18:1 in rumen bypass fat on growth performance, lipid metabolism, intestinal barrier, cecal microbiota, and inflammation in fattening bulls
BackgroundC16:0 and cis -9 C18:1 may have different effects on animal growth and health due to unique metabolism in vivo. This study was investigated...
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Melanoma risk, tumour stage, and melanoma-specific mortality in individuals with diabetes: a systematic review and meta-analysis
BackgroundCancer has become the leading diabetes-related cause of death in high-income countries, and more knowledge is needed to clarify the impact...
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Atorvastatin exerts a preventive effect against steroid-induced necrosis of the femoral head by modulating Wnt5a release
Steroid-induced osteonecrosis of the femoral head (SONFH) is a prevalent form of osteonecrosis in young individuals. More efficacious clinical...
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MicroRNAs and the Mediterranean diet: a nutri-omics perspective for lung cancer
Lung cancer is the deadliest cancer type worldwide with ~ 1.8 million deaths per-year. Smoking accounts for ~ 85% of all cases, with a described...
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Unveiling novel genetic variants in 370 challenging medically relevant genes using the long read sequencing data of 41 samples from 19 global populations
Background: A large number of challenging medically relevant genes (CMRGs) are situated in complex or highly repetitive regions of the human genome,...
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Administration and detection of a multi-target rAAV gene do** vector in horses using multiple matrices and molecular techniques
Gene do**, which includes the non-therapeutic use of genes or genetic elements that have the capacity to enhance athletic performance, is...
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Broadcasters, receivers, functional groups of metabolites, and the link to heart failure by revealing metabolomic network connectivity
Background and ObjectiveBlood-based small molecule metabolites offer easy accessibility and hold significant potential for insights into health...
