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Pain prevalence and pain relief in end-of-life care – a national registry study
BackgroundDespite pain control being a top priority in end-of-life care, pain continues to be a troublesome symptom and comprehensive data on pain...
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A comprehensive review of iatrogenic withdrawal syndrome in critically ill children
BackgroundBenzodiazepines and opioids are commonly administered to severely ill children in the pediatric intensive care unit (PICU) for analgesia...
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Impact of rehabilitation unit-based physical activity therapy versus symptomatic supportive treatment on older patients with advanced cancer: a non-randomized controlled study
ObjectivesRelatively few studies have investigated the effects of rehabilitation-based physical activity therapy as a treatment for older patients...
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Efficacy and safety of different polymyxin-containing regimens for the treatment of pneumonia caused by multidrug-resistant gram-negative bacteria: a systematic review and network meta-analysis
BackgroundThe optimal administration of polymyxins for treating multidrug-resistant gram-negative bacterial (MDR-GNB) pneumonia remains unclear. This...
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Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey
PurposeThis study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...
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Heart rate variability as a predictor of intraoperative autonomic nervous system homeostasis
The aim of the proof-of-concept study is to investigate the level of concordance between the heart rate variability (HRV), the EEG-based Narcotrend...
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Buprenorphine vs. morphine: impact on neonatal opioid withdrawal syndrome (NOWS) outcomes in a single center retrospective study
ObjectivesTo compare clinical outcomes for infants with neonatal opioid withdrawal syndrome (NOWS) treated with buprenorphine or morphine.
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Association of oral mucositis induced by anthracycline-cyclophosphamide and subsequent docetaxel treatment for perioperative breast cancer
PurposeAnthracycline-cyclophosphamide followed by docetaxel-containing chemotherapy is effective for perioperative breast cancer treatment. However,...
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Predictive enrichment for the need of renal replacement in sepsis-associated acute kidney injury: combination of furosemide stress test and urinary biomarkers TIMP-2 and IGFBP-7
BackgroundIn sepsis, initial resuscitation with fluids is followed by efforts to achieve a negative fluid balance. However, patients with...
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High comorbidity rates in congenital lobar emphysema and the effect on clinical presentation
The presence of comorbidities (CM) in congenital lobar emphysema (CLE) has been previously described with varying rates. However, the clinical...
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Mindfulness in Orthopedic Rehabilitation: Can the Use of a Mindfulness Diary Positively Influence the Therapeutic Outcome of Orthopedic Rehabilitation?
ObjectivesMindfulness is a proven therapeutic practice for reducing anxiety, depression, and chronic pain, which are factors that influence the...
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Association Between Physical Activity, Sedentary Time, and Technology Use in Autistic Adults
There is little understanding of physical activity (PA) and sedentary behavior as preventive health behaviors in autistic adults. Technology has been...
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Stability and Validity of Self-Reported Depression and Anxiety in Autistic Youth
The aim of this study was to assess test-retest reliability and diagnostic validity of self-report instruments of depression and anxiety in autistic...
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Clinical characteristics and favorable treatment responses of recurrent focal segmental glomerulosclerosis or steroid-resistant nephrotic syndrome in children after kidney transplantation
BackgroundRecurrence of focal segmental glomerulosclerosis (FSGS) or steroid-resistant nephrotic syndrome (SRNS) after kidney transplant leads to...
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Pediatric thoracic outlet syndrome: a systematic review with metadata
IntroductionThoracic outlet syndrome (TOS) typically considered a condition of the adult population; it is often disregarded in children and...
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School modality, race and ethnicity, and mental health of U.S. adolescents during the COVID-19 pandemic
BackgroundWhile minoritized ethnoracial groups were most likely to be in online learning during the COVID-19 pandemic, the impact of these...
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The effect of cesarean delivery on the neonatal gut microbiome in an under-resourced population in the Bronx, NY, USA
BackgroundNeonatal and early-life gut microbiome changes are associated with altered cardiometabolic and immune development. In this study, we...
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Enhancing sepsis biomarker development: key considerations from public and private perspectives
Implementation of biomarkers in sepsis and septic shock in emergency situations, remains highly challenging. This viewpoint arose from a...
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Hearing and speech interactions in children with cerebral palsy, in the first 2 years
AbstractChildren with cerebral palsy (CP) face communication challenges stemming from neural lesions, hearing issues, and executive function...
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Consensus-building to improve implementation of NICE guidance on planning for end-of-life treatment and care: a mixed-methods study
BackgroundDespite the availability of guidance for the provision of good end-of-life care, there are significant variations across the UK in its...