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Welches Potential hat ChatGPT 3.5 für eine qualifizierte Patienteninformation?
IntroductionThe chatbot ChatGPT represents a milestone in the interaction between humans and large databases that are accessible via the internet. It...
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Hepatitis B virus in Egypt: the whole story
Hepatitis B virus (HBV) infection is a significant global public health threat with variable geographical distribution. Chronic infection with HBV...
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Prevalence of hepatitis B among pregnant women in Libreville, Gabon
BackgroundHepatitis B virus (HBV) infection is one of the major public health problems worldwide. In pregnant women, there is a risk of...
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Cross-species transmission and histopathological variation in specific-pathogen-free minipigs infected with different hepatitis E virus strains
Hepatitis E virus (HEV) is a major cause of viral hepatitis worldwide. Pigs are the natural host of HEV genotype 3 and the main reservoir of HEV. As...
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Hepatic cholera: a case report with literature review
BackgroundVasoactive intestinal peptide-secreting tumors (VIPomas), also known as WDHA syndrome (or “pancreatic cholera”), are rare neuroendocrine...
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Exploring the complex associations among risks of malnutrition, sarcopenia, and frailty in community-dwelling older adults
BackgroundMalnutrition, sarcopenia, and frailty are age-related conditions that are associated with multiple health-related negative outcomes....
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A rare case of hepatic hydatid cyst in Somalia: a case report
BackgroundEchinococcosis, or hydatid disease, is caused by the larval forms of taeniid cestodes belonging to the genus Echinococcus . Echinococcus...
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Emerging Logistic Challenges, Health Disparities, and Bioethical Concerns in Kidney Xenotransplantation: A Literature Review
Purpose of ReviewXenotransplantation has emerged as a promising frontier in the field of kidney transplant surgery as a result of recent successful...
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Long-term survivals of immune checkpoint inhibitors as neoadjuvant and adjuvant therapy in dMMR/MSI-H colorectal and gastric cancers
BackgroundThe long-term survival benefit of immune checkpoint inhibitors (ICIs) in neoadjuvant and adjuvant settings is unclear for colorectal...
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Evaluating the performance of two different chemiluminescence analyzers systems in screening donors’ samples for HCV infection
BackgroundThe approved screening test for HCV infection among blood donors is the HCV antibody test. The diagnostic performances of the available...
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In vitro T cell responses to PD-1 blockade are reduced by IFN-α but do not predict therapy response in melanoma patients
PD-1 blockade therapy has revolutionized melanoma treatment, but still not all patients benefit and pre-treatment identification of those patients is...
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Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections
Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, modulate immune cell functions, particularly macrophages. This review...
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Blockade of the TIGIT-CD155/CD112 axis enhances functionality of NK-92 but not cytokine-induced memory-like NK cells toward CD155-expressing acute myeloid leukemia
TIGIT is an alternative checkpoint receptor (CR) whose inhibition promotes Graft-versus-Leukemia effects of NK cells. Given the significant...
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Amino acid mutations PB1-V719M and PA-N444D combined with PB2-627K contribute to the pathogenicity of H7N9 in mice
H7N9 subtype avian influenza viruses (AIVs) cause 1567 human infections and have high mortality, posing a significant threat to public health....
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Salmonella enteritidis acquires phage resistance through a point mutation in rfbD but loses some of its environmental adaptability
Phage therapy holds promise as an alternative to antibiotics for combating multidrug-resistant bacteria. However, host bacteria can quickly produce...
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Efficacy of adjuvant immune checkpoint inhibitors pembrolizumab or nivolumab in melanoma patients ≥ 75 years: results of a real-world cohort including 456 patients
BackgroundImmune checkpoint inhibitors (ICI) applied in patients with melanoma in an adjuvant setting have proven safety and efficacy in several...
