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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
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Clinical Audit of Obstetric Hysterectomy in a Tertiary Care Centre: An Observational Retroprospective Study
Purpose of StudyThe purpose of this study is to analyse the profile and characteristics of patients who may undergo obstetric hysterectomy, to study...
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Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey
PurposeThis study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...
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Safety and Efficacy of Covered Self-Expandable Metallic Stent for Choledochojejunal Anastomotic Stricture: A Multi-Center Retrospective Cohort Study
BackgroundBenign choledochojejunal anastomotic stricture (CJS) is a complication of pancreaticoduodenectomy and choledochojejunostomy. Typically...
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Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study
PurposeNeoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response...
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Clinical Investigation into Survival Outcomes Among Stage IV Epithelial Ovarian Cancer Patients Receiving Curative Treatment: Indian Setting
ObjectiveCurrently, there is scanty data regarding patients specifically with stage IV epithelial ovarian cancer (EOC) as many reports combine...
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The efficacy of early office hysteroscopy in preventing intrauterine adhesions after abortion: a randomized controlled trial
BackgroundIntrauterine adhesions (IUA) are a challenging clinical problem in reproductive infertility. The most common causes are intrauterine...
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Diagnostic Ability and Reproducibility of NICE 2017 Intrapartum Cardiotocography Interpretation Guidelines: A Prospective Observational Study
Purpose of StudyAssessment of accuracy, intra-observer and inter-observer and agreement for CTG interpretation utilizing NICE guidelines 2017.
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The impact of physical activity and exercise interventions on symptoms for women experiencing menopause: overview of reviews
BackgroundWomen experiencing problematic menopausal symptoms report lower health-related quality of life and greater healthcare use than women...
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Hyponatremia Is Associated with Mortality in Acute Pancreatitis Patients
BackgroundDisorders of serum sodium are common among general patients and are associated with poor outcomes. The prognostic value of serum sodium...
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Peripheral blood immune parameters, response, and adverse events after neoadjuvant chemotherapy plus durvalumab in early-stage triple-negative breast cancer
PurposeWe evaluated T- and B-cell receptor (TCR and BCR) repertoire diversity and 38 serum cytokines in pre- and post-treatment peripheral blood of...
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Association of oral mucositis induced by anthracycline-cyclophosphamide and subsequent docetaxel treatment for perioperative breast cancer
PurposeAnthracycline-cyclophosphamide followed by docetaxel-containing chemotherapy is effective for perioperative breast cancer treatment. However,...
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Statins for the Primary Prevention of Anthracycline Cardiotoxicity: A Comprehensive Review
Purpose of ReviewThe aim of this review is two-fold: (1) To examine the mechanisms by which statins may protect from anthracycline-induced...
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Total gonadotropin dose did not affect euploid blastocyst rates: an analysis of more than 19,000 oocytes
BackgroundTo evaluate whether increasing total gonadotropin (Gn) dose is associated with changes in euploid blastocyst rate in preimplantation...
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Reducing racial and ethnic disparities in cardiovascular outcomes among cancer survivors
Purpose of reviewAnalyze current evidence on racial/ethnic disparities in cardiovascular outcomes among cancer survivors, identifying factors and...
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Anti-apoptotic Role of Bcl-2-Associated Athanogene-3 Protein Overexpression in the Pathogenesis of Endometrial Cancers: An Aid for New Therapeutic Targets
ObjectiveBcl-2-associated athanogene-3 (BAG-3) is a cytoplasmic multidomain protein member that belongs to the BAG family of co-chaperones that are...
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