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The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff
BackgroundSharing trial results with participants is a moral imperative, but too often does not happen in appropriate ways.
MethodsWe carried out...
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A web-based video messaging intervention for suicide prevention in men: study protocol for a five-armed randomised controlled trial
BackgroundMore than 50% of people who die by suicide have not been in contact with formal mental health services. The rate of people who fly ‘under...
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Study protocol for a stepped-wedge implementation study investigating the intersectoral collaboration of implementering the TREAT INTERACT intervention for primary school teachers and the mhGAP for health care workers for child mental health promotion in Uganda
BackgroundMental and neuropsychological disorders make up approximately 14% of the total health burden globally, with 80% of the affected living in...
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Comparing the effects of low-level laser therapy and gaseous ozone as a preventive measure on medication-related osteonecrosis of the jaws following tooth extraction: a rat model
ObjectivesUse of numerous medications such as tyrosine kinase inhibitors (sunitinib), monoclonal antibodies (bevacizumab), fusion proteins...
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The relationship between community food environment around schools and student meal participation: the role of school CEP participation status
BackgroundDespite the many benefits of school meals, not all students participate. One reason students may not participate in school meals is because...
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Circulating circ_0069094 is Correlated with the Present and Endothelial Injury of Acute Coronary Syndrome
To investigate the impacts of circ_0069094 on acute coronary syndrome. Real-time polymerase chain reaction was used to detect the expression levels...
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Childhood PFAS exposure and immunotoxicity: a systematic review and meta-analysis of human studies
BackgroundExposure to poly- and perfluoroalkyl substances (PFAS) may affect infant and childhood health through immunosuppression. However, the...
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TMAO Impairs Mouse Aortic Vasodilation by Inhibiting TRPV4 Channels in Endothelial Cells
Trimethylamine oxide (TMAO) is an intestinal flora metabolite associated with risk of cardiovascular diseases. Transient receptor potential vanilloid...
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Morphological Features of the Vertebrobasilar System Predict Ischemic Stroke Risk in Spontaneous Vertebral Artery Dissection
The vertebral artery’s morphological characteristics are crucial in spontaneous vertebral artery dissection (sVAD). We aimed to investigate...
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Identification of Parkinson’s disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data
Parkinson’s disease (PD) is a serious neurodegenerative disorder marked by significant clinical and progression heterogeneity. This study aimed at...
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General skin and nasal decolonization with octenisan® set before and after elective orthopedic surgery in selected patients at elevated risk for revision surgery and surgical site infections—a single-center, unblinded, superiority, randomized controlled trial (BALGDEC trial)
BackgroundThe preoperative body surface and nasal decolonization may reduce the risk of surgical site infections (SSI) but yields conflicting results...
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Mining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning
BackgroundThe advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack...
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Impact of Active learning model and prior knowledge on discovery time of elusive relevant papers: a simulation study
Software that employs screening prioritization through active learning (AL) has accelerated the screening process significantly by ranking an...
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Factors influencing the development, recruitment, integration, retention and career development of advanced practice providers in hospital health care teams: a sco** review
BackgroundAdvanced practice providers (APPs), including physician assistants/associates (PAs), nurse practitioners (NPs) and other non-physician...
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Effect of combined physical–cognitive training on the functional and cognitive capacity of older people with mild cognitive impairment: a randomized controlled trial
BackgroundThe increase in population aging highlights the growing prevalence of mild cognitive impairment, prompting the adoption of interventions...
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A longitudinal multi-centric cohort study assessing infant neurodevelopment delay among women with persistent postpartum depression in Nepal
BackgroundInfant neurodevelopment in the first years after birth is determined by multiple factors, including parental care and maternal mental...
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The ethics of ChatGPT in medicine and healthcare: a systematic review on Large Language Models (LLMs)
With the introduction of ChatGPT, Large Language Models (LLMs) have received enormous attention in healthcare. Despite potential benefits,...
