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Pain prevalence and pain relief in end-of-life care – a national registry study
BackgroundDespite pain control being a top priority in end-of-life care, pain continues to be a troublesome symptom and comprehensive data on pain...
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Early colonic-preparation and salvage laparoscopic appendectomy (ECSLA)- innovative protocol for the management of magnets ingestion
BackgroundIngestion of magnets carries risks for significant morbidity. We propose a new protocol designed to reduce the need for surgery, shorten...
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Exploring differences in patient participation in simulated emergency cases in co-located and distributed rural emergency teams – an observational study with a randomized cross-over design
BackgroundIn northern rural Sweden, telemedicine is used to improve access to healthcare and to provide patient-centered care. In emergency care...
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The effect of plate location on radial nerve palsy recovery time associated with humeral shaft fractures
BackgroundThis study aims to investigate the influence of plate placement on nerve regeneration in humerus fractures accompanied by radial nerve...
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Perioperative management of Takotsubo cardiomyopathy: an overview
Resembling the morphology of Japanese polyp vessels, the classic form of Takotsubo cardiomyopathy is characterized by the presence of systolic...
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Evaluation of the effect of trendelenburg position duration on intracranial pressure in laparoscopic hysterectomies using ultrasonographic optic nerve sheath diameter measurements
BackgroundDuring laparoscopic surgery, pneumoperitoneum and Trendelenburg positioning applied to provide better surgical vision can cause many...
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Integrated clustering of multiple immune marker trajectories reveals different immunotypes in severely injured patients
BackgroundThe immune response of critically ill patients, such as those with sepsis, severe trauma, or major surgery, is heterogeneous and dynamic,...
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Normal saline versus Ringer’s solution and critical-illness mortality in acute pancreatitis: a nationwide inpatient database study
BackgroundFluid resuscitation is fundamental in acute pancreatitis (AP) treatment. However, the optimal choice between normal saline (NS) and...
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Impact of rehabilitation unit-based physical activity therapy versus symptomatic supportive treatment on older patients with advanced cancer: a non-randomized controlled study
ObjectivesRelatively few studies have investigated the effects of rehabilitation-based physical activity therapy as a treatment for older patients...
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Successful management of a delayed presentation of traumatic descending thoracic aorta pseudoaneurysm: a literature review based on a case report
BackgroundBlunt traumatic aortic injury (BTAI) is the second leading cause of death due to traumas in young patients. The primary presentation might...
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Evaluation of postoperative results after a presurgical optimisation programme
BackgroundPresurgical optimisation programmes decrease the risk of postoperative complications, reduce hospital stays and speed up patient recovery....
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The use of point of care gastric ultrasound and anesthesia management in pediatric patients with preoperative fasting non-adherence scheduled for elective surgical procedures: a retrospective study
BackgroundFailure to adhere to perioperative fasting requirements increases aspiration risk and can lead to delay or cancellation of surgery. Point...
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PHF6 suppresses self-renewal of leukemic stem cells in AML
Acute myeloid leukemia is characterized by uncontrolled proliferation of self-renewing myeloid progenitors accompanied by a differentiation arrest....
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Efficacy and safety of different polymyxin-containing regimens for the treatment of pneumonia caused by multidrug-resistant gram-negative bacteria: a systematic review and network meta-analysis
BackgroundThe optimal administration of polymyxins for treating multidrug-resistant gram-negative bacterial (MDR-GNB) pneumonia remains unclear. This...
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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
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Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey
PurposeThis study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...
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Predictive enrichment for the need of renal replacement in sepsis-associated acute kidney injury: combination of furosemide stress test and urinary biomarkers TIMP-2 and IGFBP-7
BackgroundIn sepsis, initial resuscitation with fluids is followed by efforts to achieve a negative fluid balance. However, patients with...
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Heart rate variability as a predictor of intraoperative autonomic nervous system homeostasis
The aim of the proof-of-concept study is to investigate the level of concordance between the heart rate variability (HRV), the EEG-based Narcotrend...
