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Forensic significance of VOCs profiling in decayed ante- and post-mortem injuries by GC×GC-TOF/MS
Accurately identifying and differentiating the types of injuries in decomposed corpses is a major challenge in forensic identification. Forensic...
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A case of death after the severing three appendiceal arteries during appendectomy
IntroductionAcute appendicitis is one of the most common acute abdominal issues requiring surgery and is usually treated by appendectomy. During the...
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Targeting the pancreatic tumor microenvironment by plant-derived products and their nanoformulations
Pancreatic cancer remains a significant health issue with limited treatment options. The tumor stroma, a complex environment made up of different...
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Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases
Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether...
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Soft tissue hemangioma of the right upper extremity with intraosseous extension and secondary intravascular papillary endothelial hyperplasia
Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson’s tumor, is an uncommon exuberant form of organizing thrombus that may...
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Combined neurokinin-1 receptor antagonist and sorafenib is a promising approach for hepatocellular carcinoma therapy
BackgroundHCC (Hepatocellular carcinoma) is the most common primary malignant cancer in the liver. Treatment options to incurable HCC such as...
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Contemporary review of papillary renal cell carcinoma—current state and future directions
Historically, papillary renal cell carcinoma (PRCC) was divided into two types, type 1 and type 2, based solely on morphology. However, it is...
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DNA methylation patterns in the frontal lobe white matter of multiple system atrophy, Parkinson’s disease, and progressive supranuclear palsy: a cross-comparative investigation
Multiple system atrophy (MSA) is a rare neurodegenerative disease characterized by neuronal loss and gliosis, with oligodendroglial cytoplasmic...
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Anti-cancer potential of casein and its derivatives: novel strategies for cancer treatment
Cancer is one of the leading causes of death worldwide, with over 10 million fatalities annually. While tumors can be surgically removed and treated...
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Pediatric thyroid-like follicular renal cell carcinoma—a post-neuroblastoma case with comprehensive genomic profiling data
Thyroid-like follicular renal cell carcinoma (TLFRCC), an emerging subtype of renal cell carcinoma, presents diagnostic challenges due to its...
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Comprehensive analysis of transcription factors involved in odontoblast differentiation mechanism
Primary cultured odontoblasts rapidly lose their tissue-specific phenotype. To identify transcription factors (TF) that are important for the...
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Immunohistochemistry staining of Eag1 and p16/Ki-67 can help improve the management of patients with cervical intraepithelial Neoplasia after cold knife conversion
BackgroundImmunohistochemistry (IHC) is widely used in the management of patients with cervical intraepithelial neoplasia (CIN) but still has many...
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Stability of new psychoactive substances in crude wastewater
Those involved in drug testing continue to grapple with the dynamic nature of emerging psychoactive substances (NPS) and their rapid infiltration...
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Hepatitis B virus in Egypt: the whole story
Hepatitis B virus (HBV) infection is a significant global public health threat with variable geographical distribution. Chronic infection with HBV...
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Dynamic ultrasound assessment for insertional achilles tendinopathy: the COcco-RIcci (CORI) sign
ObjectiveTo describe a novel, dynamic ultrasound assessment of the Achilles tendon at the calcaneal insertion taking advantage of the effusion within...
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Situs inversus partialis (levocardia): an incidental discovery of an extremely rare case during the autopsy of a female with suicidal poisoning
BackgroundSitus inversus is a rare congenital anomaly. In this condition, the abdominal and chest organs are positioned in reverse, a mirror image of...
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