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Doing a double take: when transthoracic echocardiography fails for mitral valve annuloplasty ring endocarditis with Streptococcus pyogenes: a case report
BackgroundThis case highlights several complications of a late and rare presentation of culture-negative Streptococcus pyogenes endocarditis of a...
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Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis
BackgroundAll orthopaedic procedures, comprising foot and ankle surgeries, seemed to show a positive trend, recently. Bone grafts are commonly...
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Emerging biologic augmentation strategies for meniscal repair: a systematic review
BackgroundMeniscal repair should be the gold standard. However, the meniscus is poorly vascularized and even an excellent meniscus repair may not...
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Evaluating a National Academic Mentorship Program to Grow the Next Generation of Gender-based Violence Intervention and Prevention (VIP) Researchers
PurposeThe personal, economic, and societal costs and consequences of gender-based violence are significant. Although much violence intervention and...
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Young People’s Barriers and Facilitators of Engagement with Web-Based Mental Health Interventions for Anxiety and Depression: A Qualitative Study
BackgroundThe prevalence of anxiety and depressive symptoms in young people have increased in many countries around the world. Web-based mental...
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Diffusion-tensor magnetic resonance imaging as a non-invasive assessment of extracellular matrix remodeling in lumbar paravertebral muscles of rats with sarcopenia
BackgroundExtracellular matrix (ECM) remodeling in skeletal muscle is a significant factor in the development of sarcopenia. This study aims to...
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Ocular manifestations in ANCA-associated vasculitis: a comprehensive analysis from Chinese medical centers
IntroductionThis study aimed to explore ocular manifestations in ANCA-associated vasculitis (AAV), focusing on granulomatosis with polyangiitis...
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Scale and rate heterogeneity in the EQ-5D-5L valuation
ObjectivesTo estimate values on a quality-adjusted life year (QALY) scale using individual preference evidence, choice analyses typically include...
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Stable Response and Sustained Improvement of Itch and Sleep Symptoms in Patients with Atopic Dermatitis Treated with Lebrikizumab over 52 Weeks
BackgroundLebrikizumab demonstrated significant improvement versus placebo for measures of skin clearance and patient-reported outcomes at weeks 16...
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Multiple lung abscesses and cold agglutinin syndrome following coronavirus disease 2019: a case report
BackgroundCold agglutination syndrome is a subtype of autoimmune hemolytic anemia. The condition is referred to as “cold” because the antibodies...
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Anti-α-1,4-D-polygalacturonic acid antibodies as a new biomarker for juvenile idiopathic arthritis
ObjectiveDiagnosing juvenile idiopathic arthritis (JIA) is challenging. Our study aimed to investigate the clinical significance of...
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Prioritizing drug targets in systemic lupus erythematosus from a genetic perspective: a druggable genome-wide Mendelian randomization study
ObjectivesSystemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with an unsatisfactory state of treatment. We aim to explore novel...
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“So Just with every Facet, Every Side of this Journey, They Have Somebody Walking alongside with Them”: Practitioners’ Perspectives of the Lethality Assessment Program as a Collaborative Model
PurposeAscriticism of the criminalization of domestic violence (DV) has gained momentum, programs such as the Lethality Assessment Program (LAP)...
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Consensus-building to improve implementation of NICE guidance on planning for end-of-life treatment and care: a mixed-methods study
BackgroundDespite the availability of guidance for the provision of good end-of-life care, there are significant variations across the UK in its...
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Olfactory Dysfunction in Chronic Rhinosinusitis
Purpose of reviewChronic rhinosinusitis (CRS) is a prevalent and heterogeneous inflammatory disease that affects millions of people worldwide....
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Predictors of High Healthcare Cost Among Patients with Generalized Myasthenia Gravis: A Combined Machine Learning and Regression Approach from a US Payer Perspective
BackgroundHigh healthcare costs could arise from unmet needs. This study used random forest (RF) and regression methods to identify predictors of...
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Non-osteoporotic fractures are associated with increased risk of subsequent major osteoporotic fractures
SummaryWe studied the association between non-osteoporotic fractures and future major osteoporotic fractures, using UK health records....
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Specialized expertise among healthcare professionals in palliative care - A sco** review
BackgroundThe generalist-plus-specialist palliative care model is endorsed worldwide. In the Netherlands, the competencies and profile of the...
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COVID-19 severity, breakthrough infections and vaccine safety in young individuals with autoimmune diseases: insights from the COVAD study
Notwithstanding the wealth of literature on COVID-19, studies focusing on young adults with autoimmune diseases (AD) are lacking. To determine early...
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Serum GM-CSF level is a predictor of treatment response to tocilizumab in rheumatoid arthritis patients: a prospective observational cohort study
BackgroundThe aim of this prospective observational cohort study was to unveil the predictors of treatment response to tocilizumab (TCZ) therapy in...
