Search
Search Results
-
SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study
A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...
-
Map** alternative splicing events in colorectal cancer
Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal...
-
Risk factors associated with underweight in children aged one to two years: a longitudinal study
BackgroundUnderweight is a prevalent health issue in children. This study aimed to identify factors associated with underweight in children aged 1–2...
-
Perception of couples’ on multipurpose prevention technology attribute choice: the case of MTN 045
BackgroundMultipurpose prevention technologies (MPTs) are products capable of simultaneously addressing multiple sexual and reproductive health needs...
-
Detection and characterization of autoreactive memory stem T-cells in children with acute immune thrombocytopenia
Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by an isolated decrease in platelets below 100 × 10 9 /l after...
-
Mavorixafor: First Approval
Mavorixafor (XOLREMDI™) is an oral, selective C-X-C chemokine receptor 4 (CXCR4) antagonist developed by X4 Pharmaceuticals that blocks the binding...
-
Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses
BackgroundNivolumab monotherapy is the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC) after failure of...
-
Effect of dorsal capsular imbrication on intraoperative DRUJ instability following arthroscopic TFCC repair surgery
BackgroundTo assess the clinical outcomes and identify the ideal indication for implementing dorsal distal radioulnar joint (DRUJ) capsular...
-
Evaluation of the clinical efficacy of using an inverted triangular cannulated compression screw in combination with positive or negative buttress reduction for the healing of femoral neck fractures
ObjectiveWe aimed to compare the clinical efficacy of inverted triangular cannulated compression screws combined with Gotfried positive or negative...
-
Effect of recurrent severe insulin-induced hypoglycemia on the cognitive function and brain oxidative status in the rats
BackgroundEpisodes of recurrent or severe hypoglycemia can occur in patients with diabetes mellitus, insulinoma, neonatal hypoglycemia, and...
-
-
Epidemiology, outcomes and prognosis of infective endocarditis in Northern Morocco
IntroductionInfective endocarditis is a rare but potentially severe disease, associated with significant morbidity and mortality. Our study aims to...
-
Sex ratio at birth across 100 years in Sweden and risk of cardiovascular disease and all-cause mortality – a national register study
The human sex ratio at birth (SRB) undergoes temporary changes around a mean proportion of 0.51 male births. SRB has been well studied for...
-
Assessment of glycemic susceptibility across multiple urological and reproductive disorders
ObjectiveTo test the glycemic susceptibility in three urological cancers and eight urological/reproductive diseases using the Mendelian randomization...
-
Impact on Glycemia Risk Index and other metrics in type 1 adult patients switching to Advanced Hybrid Closed-Loop systems: a one-year real-life experience
BackgroundAdvanced Hybrid Closed-Loop system (AHCL) has profoundly changed type 1 diabetes therapy. This study primarily aimed to assess the impact...
-
Predictors of response to Radioactive Iodine Therapy in Intermediate and high risk patients with papillary thyroid carcinoma
BackgroundRadioactive iodine (RAI) therapy is the standard treatment approach after total thyroidectomy in patients with papillary thyroid carcinoma...
-
-
Estimated Incidence of Hospitalizations Attributable to RSV Infection Among Adults in Ontario, Canada, Between 2013 and 2019
IntroductionAdult respiratory syncytial virus (RSV) burden is underestimated due to non-specific symptoms, limited standard-of-care and delayed...
-
Effects of major air pollutants on angina hospitalizations: a correlation study
BackgroundAngina is a crucial risk signal for cardiovascular disease. However, few studies have evaluated the effects of ambient air pollution...
