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  1. Detection and characterization of autoreactive memory stem T-cells in children with acute immune thrombocytopenia

    Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by an isolated decrease in platelets below 100 × 10 9 /l after...

    Asmaa M. Zahran, Omnia H. El-Badawy, ... Khalid I. Elsayh in Clinical and Experimental Medicine
    Article Open access 15 July 2024

  2. Evaluating [225Ac]Ac-FAPI-46 for the treatment of soft-tissue sarcoma in mice

    Purpose

    Fibroblast Activation Protein (FAP) is an emerging theranostic target that is highly expressed on cancer-associated fibroblasts and on certain...

    Marco F. Taddio, Suraj Doshi, ... Christine E. Mona in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 15 July 2024

  3. Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses

    Background

    Nivolumab monotherapy is the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC) after failure of...

    Yuko Murashima, Shun Yamamoto, ... Ken Kato in Journal of Gastrointestinal Cancer
    Article Open access 15 July 2024

  5. Interrelationship between thyroid hormones and reduced renal function, a review article

    Background

    Understanding the relationship of thyroid hormones with the development of chronic kidney disease (CKD) has important clinical implications...

    Sadaf Agahi, Atieh Amouzegar, ... Ladan Mehran in Thyroid Research
    Article Open access 15 July 2024

  6. SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study

    A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...

    Ziming Li, Zhengbo Song, ... Shun Lu in Signal Transduction and Targeted Therapy
    Article Open access 15 July 2024

  7. Map** alternative splicing events in colorectal cancer

    Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal...

    Yifeng Zheng, Guoqiang Zhong, ... Mingsong Li in Discover Oncology
    Article Open access 15 July 2024

  8. Preclinical SPECT and PET: Joint EANM and ESMI procedure guideline for implementing an efficient quality control programme

    The aim of this guideline is to provide recommendations for the implementation of an effective and efficient quality control (QC) programme for SPECT...

    Christian Vanhove, Michel Koole, ... Monique Bernsen in European Journal of Nuclear Medicine and Molecular Imaging
    Article 15 July 2024

  9. Cardiovascular events in CML patients treated with Nilotinib: validation of the HFA-ICOS baseline risk score

    Background

    The therapeutic landscape of chronic myeloid leukaemia (CML) has been transformed by tyrosine kinase inhibitors (TKI). Nilotinib, showed...

    Fiona Fernando, Maria Sol Andres, ... Dragana Milojkovic in Cardio-Oncology
    Article Open access 15 July 2024

  11. ACTH-producing adrenocortical carcinoma: an exceedingly rare diagnosis

    Background

    Adrenocortical carcinoma is a very rare endocrinopathy that has a poor prognosis and is frequently associated with ACTH-independent...

    Miguel Saraiva, Raquel da Inez Correia, ... Isabel Palma in Journal of the Egyptian National Cancer Institute
    Article Open access 15 July 2024

  12. Sex ratio at birth across 100 years in Sweden and risk of cardiovascular disease and all-cause mortality – a national register study

    The human sex ratio at birth (SRB) undergoes temporary changes around a mean proportion of 0.51 male births. SRB has been well studied for...

    Peter M. Nilsson, Kristina Sundquist, ... **njun Li in European Journal of Epidemiology
    Article Open access 15 July 2024

  13. Impact on Glycemia Risk Index and other metrics in type 1 adult patients switching to Advanced Hybrid Closed-Loop systems: a one-year real-life experience

    Background

    Advanced Hybrid Closed-Loop system (AHCL) has profoundly changed type 1 diabetes therapy. This study primarily aimed to assess the impact...

    Eugenia Resmini, Emanuela Zarra, ... Angela Girelli in European Journal of Medical Research
    Article Open access 15 July 2024

  18. YAP/TAZ interacts with RBM39 to confer resistance against indisulam

    The Hippo pathway and its downstream effectors, Yes-associated protein/transcriptional coactivator with PDZ-binding motif (YAP/TAZ), are essential...

    Toshinori Ando, Kento Okamoto, ... Mikihito Kajiya in Oncogenesis
    Article Open access 15 July 2024

  19. Impact of rehabilitation unit-based physical activity therapy versus symptomatic supportive treatment on older patients with advanced cancer: a non-randomized controlled study

    Objectives

    Relatively few studies have investigated the effects of rehabilitation-based physical activity therapy as a treatment for older patients...

    **aoqiong Lu, Shubao Wei, ... **uqiong Chen in Supportive Care in Cancer
    Article Open access 15 July 2024
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