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Ubiquitin recruiting chimera: more than just a PROTAC
Ubiquitinylation of protein substrates results in various but distinct biological consequences, among which ubiquitin-mediated degradation is most...
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Tragia grandistipularis (Euphorbiaceae), a new species from Malawi
We describe and illustrate Tragia grandistipularis (Euphorbiaceae), a new species from the Southern Region of Malawi, which is easily distinguished...
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The bulk of a plant hotspot: composition, species richness and conservation status of the Cerrado herbaceous–subshrub flora
The Cerrado is a Neotropical savanna with the highest plant species richness among tropical savannas. Most of these species are herbs and subshrubs,...
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Beauveria bassiana native strains affect the reproductive index of Rhipicephalus microplus ticks
Rhipicephalus microplus poses a significant economic threat due to its role in transmitting Babesia bigemina, B. bovis and Anaplasma marginale ....
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Green synthesis of zinc oxide nanoparticles (ZnO-NPs) by Streptomyces baarnensis and its active metabolite (Ka): a promising combination against multidrug-resistant ESKAPE pathogens and cytotoxicity
Various eco-friendly techniques are being researched for synthesizing ZnO-NPs, known for their bioactivity. This study aimed at biosynthesizing...
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Effects of temperature gradient on functional fruit traits: an elevation-for-temperature approach
Fruit traits mediate animal-plant interactions and have to a large degree evolved to match the sensory capacities and morphology of their respective...
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Evaluating the probiotic effects of spraying lactiplantibacillus plantarum P-8 in neonatal piglets
BackgroundGut microbes play an important role in the growth and health of neonatal piglets. Probiotics can promote the healthy growth of neonatal...
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Detection and molecular characterization of soft scale insect, Megapulvinaria maxima (Green) (Hemiptera: Coccidae) infesting Gymnema sylvestre (Retz.) R.Br. ex Sm. from India
Gymnema sylvestre (Retz.) R. Br. ex Sm is a vital medicinal plant effective in treatment of Diabetes mellitus. The soft scale, Megapulvinaria maxima (...
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Temporal and spatial variation in the direct and indirect effects of climate on reproduction in alpine populations of Ranunculus acris L
Plant reproduction in alpine environments is affected by climate both directly through climate impacts on growth and phenology, and indirectly...
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Turbidity effects on prey consumption and survival of larval European smelt (Osmerus eperlanus)
The anadromous European smelt ( Osmerus eperlanus ) plays a key role in food webs of many riverine ecosystems in Europe. However, population sizes in...
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Genetic diversity studies of Baikal endemic sponges at the interspecies and population levels using high-resolution microsatellite markers
Lake Baikal, an ancient, massive lake in Siberia that holds 20% of the world’s fresh water reserves, is a unique center of speciation. Changes in the...
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ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction
Z-DNA binding protein 1 (ZBP1) is a crucial player in the intracellular recognition of Z-form nucleic acids (Z-NAs) through its Zαβ domain,...
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Comparative proteomics in tall fescue to reveal underlying mechanisms for improving Photosystem II thermotolerance during heat stress memory
BackgroundThe escalating impacts of global warming intensify the detrimental effects of heat stress on crop growth and yield. Among the earliest and...
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Targeting BRD4 mitigates hepatocellular lipotoxicity by suppressing the NLRP3 inflammasome activation and GSDMD-mediated hepatocyte pyroptosis
Nod-like receptor family pyrin-containing protein 3 (NLRP3) inflammasome plays a pathologic role in metabolic dysfunction-associated steatohepatitis...
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Moderate beta-cell ablation triggers synergic compensatory mechanisms even in the absence of overt metabolic disruption
Regeneration, the ability to replace injured tissues and organs, is a phenomenon commonly associated with lower vertebrates but is also observed in...
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Simultaneous de novo calling and phasing of genetic variants at chromosome-scale using NanoStrand-seq
The successful accomplishment of the first telomere-to-telomere human genome assembly, T2T-CHM13, marked a milestone in achieving completeness of the...
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Population structure and selection signal analysis of indigenous sheep from the southern edge of the Taklamakan Desert
Analyzing the genetic diversity and selection characteristics of sheep (Ovis aries) holds significant value in understanding their environmental...
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Understanding the responses of tillering to 2,4-D isooctyl ester in Setaria viridis L.
BackgroundGreen foxtail [ Setaria viridis (L.)] is one of the most abundant and troublesome annual grass weeds in alfalfa fields in Northeast China....
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Chrysin-loaded PEGylated liposomes protect against alloxan-induced diabetic neuropathy in rats: the interplay between endoplasmic reticulum stress and autophagy
BackgroundDiabetic neuropathy (DN) is recognized as a significant complication arising from diabetes mellitus (DM). Pathogenesis of DN is accelerated...
