Search
Search Results
-
DAP12 interacts with RER1 and is retained in the secretory pathway before assembly with TREM2
DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed in lymphoid and myeloid lineage cells. It interacts with...
-
Heritability and correlations for honey yield, handling ease, brood quantity, and traits related to resilience in a French honeybee population
There is growing interest in selective breeding of the honeybee, resulting in the emergence of new breeding projects, often with an emphasis on...
-
Cattleya attenboroughiana (Orchidaceae: Laeliinae): a new species from the Diamantina Plateau, Minas Gerais, Brazil
A new species of Cattleya ser. Parviflorae (Orchidaceae) is here described from the campos rupestres of the Diamantina Plateau, part of the Espinhaço...
-
p53 at the crossroads of tumor immunity
The p53 tumor suppressor protein has a plethora of cell-intrinsic functions and consequences that impact diverse cell types and tissues. Recent...
-
Long-term biotic homogenization in the East African Rift System over the last 6 million years of hominin evolution
Eastern Africa preserves the most complete record of human evolution anywhere in the world but we have little knowledge of how long-term...
-
The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation
Multiple neurodegenerative diseases are characterized by aberrant proteinaceous accumulations of tau. Here, we report a RING-in-between-RING-type E3...
-
Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition
Therapy resistance and metastasis, the most fatal steps in cancer, are often triggered by a (partial) activation of the epithelial–mesenchymal...
-
Building a translational cancer dependency map for The Cancer Genome Atlas
Cancer dependency maps have accelerated the discovery of tumor vulnerabilities that can be exploited as drug targets when translatable to patients....
-
Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health
Glutamine and glutamate are interconverted by several enzymes and alterations in this metabolic cycle are linked to cardiometabolic traits. Herein,...
-
Vitamin C inactivates c-Jun N-terminal kinase to stabilize heart and neural crest derivatives expressed 1 (Hand1) in regulating placentation and maintenance of pregnancy
Vitamin C (VC) serves as a pivotal nutrient for anti-oxidation process, metabolic responses, and stem cell differentiation. However, its precise...
-
Map** of Aegilops speltoides derived leaf rust and stripe rust resistance genes using 35K SNP array
Wheat is an essential food commodity cultivated throughout the world. However, this crop faces continuous threats from fungal pathogens, leaf rust...
-
FADD regulates adipose inflammation, adipogenesis, and adipocyte survival
Adipose tissue, aside from adipocytes, comprises various abundant immune cells. The accumulation of low-grade chronic inflammation in adipose tissue...
-
Effect of vegetation cover and soil moisture on water repellency persistence of drained peat soils
Peatlands play an essential role in the environment and their conservation requires knowledge of water-related processes. Their hydrophobicity is an...
-
Aquatic deoxygenation as a planetary boundary and key regulator of Earth system stability
Planetary boundaries represent thresholds in major Earth system processes that are sensitive to human activity and control global-scale habitability...
-
-
Transition of survival strategies under global climate shifts in the grape family
Faced with environmental changes, plants may either move to track their ancestral niches or evolve to adapt to new niches. Vitaceae, the grape...
-
-
MHC class II proteins mediate sialic acid independent entry of human and avian H2N2 influenza A viruses
Influenza A viruses (IAV) pose substantial burden on human and animal health. Avian, swine and human IAV bind sialic acid on host glycans as...
