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Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic acid cycle and subsequent loss of iron-sulfur cluster...
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Elucidating CTLA-4’s role in tumor immunity: a comprehensive overview of targeted antibody therapies and clinical developments
Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) emerges as a key single-chain transmembrane glycoprotein predominantly expressed in effector T...
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Reactive oxygen species and depolarization the inner mitochondrial membrane under effect of synthetic auxin herbicides in plant cell culture of Arabidopsis thaliana L.
The cytotoxic effect of synthetic analogs of auxins, namely 2.4-D and clopyralid on heterotrophic cell suspension culture of Arabidopsis thaliana ,...
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Goat weed (Ageratum conyzoides L.): A biological threat to plant diversity in Eastern Ghats of India
The Kunming–Montreal Global Biodiversity Framework (GBF) is a recently signed protocol by the conference of the parties (COP 15) with an aim to...
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CRISPR/Cas9-mediated genome editing technique to control fall armyworm (Spodoptera frugiperda) in crop plants with special reference to maize
Fall Armyworm imposes a major risk to agricultural losses. Insecticides have historically been used to manage its infestations, but it eventually...
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Synthesis, Characterization, Phytochemistry, and Therapeutic Potential of Azadirachta indica Conjugated Silver Nanoparticles: A Comprehensive Study on Antidiabetic and Antioxidant Properties
Nanotechnology has become a major topic of study, particularly in the medical and health domains. Because nanomedicine has a higher recovery rate...
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An Investigation on the Present Status of Wetlands in Majuli River Island; The World Largest River Island and Its Fishery Resources
Wetlands are widely known for its distinctive and most diverse ecosystems in the world. Assam is blessed with number of lentic systems . The beels are...
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Genome-wide identification and expression analysis of the SOD gene family under biotic and abiotic stresses in sweet orange
Superoxide dismutase (SOD) protects plants from biotic and abiotic stress-induced reactive oxygen species toxicity and is extensively involved in...
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Influence of Suppressor of Cytokine Signaling 1 (SOCS1) Gene Variations on Polycystic Ovary Syndrome
Polycystic ovarian syndrome (PCOS) is associated with low-grade systemic inflammation and an increase in inflammation markers, which are crucial in...
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Accuracy of prediction from multi-environment trials for new locations using pedigree information and environmental covariates: the case of sorghum (Sorghum bicolor (L.) Moench) breeding
Key messagesWe investigate a method of extracting and fitting synthetic environmental covariates and pedigree information in multilocation trial data...
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Association between dietary (poly)phenol intake and the ATHLOS Healthy Ageing Scale in the Polish arm of the HAPIEE study
Inverse association between (poly)phenol intake and age-related disorders has been demonstrated; however, little is known whether they affect...
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Unveiling the mechanism of essential oil action against skin pathogens: from ancient wisdom to modern science
Essential oils are among the most well-known phyto-compounds, and since ancient times, they have been utilized in medicine. Over 100 essential oils...
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LINC01133 promotes pancreatic ductal adenocarcinoma epithelial–mesenchymal transition mediated by SPP1 through binding to Arp3
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with limited treatment methods. Long non-coding RNAs (lncRNAs) have been found involved...
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Proteome profiling, biochemical and histological analysis of diclofenac-induced liver toxicity in Yersinia enterocolitica and Lactobacillus fermentum fed rat model: a comparative analysis
Diclofenac is a hepatotoxic non-steroidal anti-inflammatory drug (NSAID) that affects liver histology and its protein expression levels. Here, we...
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Autotaxin Inhibition Reduces Post‐Ischemic Myocardial Inflammation via Epigenetic Gene Modifications
Myocardial infarction (MI) triggers a complex inflammatory response that is essential for cardiac repair but can also lead to adverse outcomes if...
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Pathogenesis of cardiovascular diseases: effects of mitochondrial CF6 on endothelial cell function
Cardiovascular disease (CVD) stands as a predominant global cause of morbidity and mortality, necessitating effective and cost-efficient therapies...
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Mutational Improvement of the Lactobacillus delbrueckii subsp. lactis Biopreservation Potential
AbstractThe primary objective of this study was to develop tools and strategies aimed at enhancing the synthesis of hydrogen peroxide in Lactobacillus...
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LSPR-based Colorimetric Aptasensor Design for Rapid and Simple Detection of Vibrio cholerae O1
AbstractIn recent years, the prevalence of intestinal diseases, particularly Vibrio cholerae , has been on the rise, leading to numerous epidemics...
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Pathophysiological role of Na–Cl cotransporter in kidneys, blood pressure, and metabolism
The Na–Cl cotransporter (NCC) is a well-recognized regulator of ion transportation in the kidneys that facilitates Na + reabsorption in the distal...
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Biochemical Characterization and Electrochemical Cultivation of Halotolerant Autotrophic Iron-Oxidizing Bacteria Isolated from Electroplating Wastewater Sludge in Japan
AbstractThe aerobic and rod-shaped FO1 strain of iron-oxidizing bacteria was isolated from electroplating wastewater sludge using colloidal silica...
