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A stochastic approach for parameter optimization of feature detection algorithms for non-target screening in mass spectrometry
Feature detection plays a crucial role in non-target screening (NTS), requiring careful selection of algorithm parameters to minimize false positive...
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Externally supplied ascorbic acid moderates detrimental effects of UV-C exposure in cyanobacteria
The defensive role performed by exogenously supplied ascorbic acid in the cyanobacterium Nostoc muscorum Meg1 against damages produced by UV-C...
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Progress, applications, and challenges in high-throughput effect-directed analysis for toxicity driver identification — is it time for HT-EDA?
The rapid increase in the production and global use of chemicals and their mixtures has raised concerns about their potential impact on human and...
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Quantitative comparison of bile acid glucuronides sub-metabolome between intrahepatic cholestasis and healthy pregnant women
Because of the pathological indication and the physiological functions, bile acids (BAs) have occupied the research hotspot in recent decades....
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Design, synthesis, characterization, and docking studies of hiherto unkown chlorinated thiazolidine, thiophene, and 2-iminochromene derivatives as protein-like protease inhibitors
The present work details the synthesis of several intriguing nitrogenous heterocycles utilizing a cyano- N -aryl-acetamide-reagent, notably chlorinated...
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Highly Thermal Tunable Propagating Surface Plasmons on Supported Semiconductor Nanowire Metamaterial
It is generally known for metal nanoparticles and metal surfaces that surface plasmons, or the quanta of the collective oscillations of free...
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Research Progress of ARTP Mutagenesis Technology Based on Citespace Visualization Analysis
Atmospheric and room temperature plasma (ARTP) mutagenesis technology has been developed rapidly in recent years because of its simple operation,...
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Green synthesis and characterization of zinc oxide nanoparticles using Monoon longifolium leave extract for biological applications
The present study deals with the biosynthesis of zinc oxide nanoparticles (ZnO NPs) using the Monoon longifolium ( M . longifolium ) leaf extract. The...
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Facile preparation of Ni-Hg-Fe amalgam for hydrogen evolution reaction in NaOH solution
An alloy of Ni-Hg-Fe was synthesized on a graphite electrode using direct current electrodeposition to facilitate the hydrogen evolution reaction...
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Intramolecular [π4s + π4s] photocycloaddition of carbon- and nitrogen-bridged [32](1,4)naphthalenophanes
[3 2 ](1,4)Naphthalenophanes, bearing carbon-bridge chains ( syn - and anti - NPs ) and nitrogen-bridge chains ( syn - and anti - ANPs ), were synthesized, and...
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Establishment of a multi-line immunochromatography based on magnetic nanoparticles for simultaneous screening of multiple biomarkers
Biomarkers screening is a benefit approach for early diagnosis of major diseases. In this study, magnetic nanoparticles (MNPs) have been utilized as...
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Rapid analysis of untreated food samples by gel loading tip spray ionization mass spectrometry
Rapid, efficient, versatile, easy-to-use, and non-expensive analytical approaches are globally demanded for food analysis. Many ambient ionization...
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Oncogenic Gene CNOT7 Promotes Progression and Induces Poor Prognosis of Glioma
Glioma is the most common malignant brain tumor in the central nervous system with the poor prognosis of patients. The CNOT7 (CCR4-NOT Transcription...
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Design and Numerical Analysis of a Fractal Tree Shaped Graphene Based Metasurface Solar Absorber
This study introduces a novel solar absorber design using a fractal tree-shaped graphene-based metasurface. The absorber structure consists of...
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Expression, Purification and Biophysical Characterisation of Klebsiella Pneumoniae Protein Adenylyltransferase: A Systematic Integration of Empirical and Computational Modelling Approaches
Infections that are acquired due to a prolonged hospital stay and manifest 2 days following the admission of a patient to a health-care institution...
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Genomic Insights into the Landfill Microbial Community: Denitrifying Activity Supporting One-Carbon Utilization
In spite of the developments in understanding of denitrifying methylotrophy in the recent years, challenges still exist in unravelling the overall...
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KIAA1429 promotes the malignancy of oral squamous cell carcinoma by regulating CA9 m6A methylation
KIAA1429 has been reported as a cancer regulator, but its role and mechanism in the progression of oral squamous cell carcinoma (OSCC) remain...
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Probing Dual Covalent Irreversible Inhibition of EGFR/FGFR4 by Electrophilic-Based Natural Compounds to Overcome Resistance and Enhance Combination Therapeutic Potentials and Management of Hepatocellular Carcinoma (HCC)
Hepatocellular carcinoma (HCC) is one of the most prevalent cancer types in the world and accounts for the majority of cases of primary liver cancer....
