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Evaluation of chimeric recombinant antigens for the serodiagnosis of Trypanosoma cruzi in dogs: a promising tool for Chagas disease surveillance
BackgroundChagas disease (CD), a neglected parasitic disease caused by Trypanosoma cruzi , poses a significant health threat in Latin America and has...
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The C-terminal region of the Plasmodium berghei gamete surface 184-kDa protein Pb184 contributes to fertilization and male gamete binding to the residual body
BackgroundMalaria, a global health concern, is caused by parasites of the Plasmodium genus, which undergo gametogenesis in the midgut of mosquitoes...
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Malaria prevalence and transmission in the Zakpota sub-district of central Benin: baseline characteristics for a community randomised trial of a new insecticide for indoor residual spraying
BackgroundMalaria transmission is known to be perennial and heterogeneous in Benin. Studies assessing local malaria prevalence, transmission levels...
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Efficacy of Interceptor G2, Royal Guard and PermaNet 3.0 against pyrethroid-resistant Anopheles gambiae s.l. from Za-Kpota, southern Benin: an experimental hut trial
BackgroundThe widespread use of insecticide-treated nets (ITNs) has significantly contributed to the reduction in malaria cases and deaths observed...
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Human Babesia odocoilei and Bartonella spp. co-infections in the Americas
BackgroundIn recent years, Babesia and Bartonella species co-infections in patients with chronic, nonspecific illnesses have continued to challenge...
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Development of microsatellite markers for the soft tick Ornithodoros phacochoerus
BackgroundSoft ticks of the genus Ornithodoros are responsible for the maintenance and transmission of the African swine fever (ASF) virus in the...
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The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy
BackgroundToxoplasma gondii infection causes adverse pregnancy outcomes by affecting the expression of immunotolerant molecules in decidual immune...
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High rates of benzimidazole-resistance-associated alleles in Haemonchus contortus and detection of resistance against macrocyclic lactones in strongylids from German alpaca herds
The population of South American camelids (SAC) has been steadily growing in Europe, where they are confronted with the regional endoparasite...
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Description of Babesia galileei sp. nov. A Piroplasmid species causing severe disease in domestic cats
BackgroundBabesiosis is a tick-borne infection caused by piroplasmid protozoa and associated with anemia and severe disease in humans, domestic...
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Effect of Microsporidia MB infection on the development and fitness of Anopheles arabiensis under different diet regimes
BackgroundMicrosporidia MB ( MB ) is a naturally occurring symbiont of Anopheles and has recently been identified as having a potential to inhibit the...
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A new diagnostic technique for identifying Angiostrongylus spp. larvae in intermediate snail species by examining the buccal cavity
BackgroundAngiostrongyliasis is a zoonotic parasitic disease caused by the rat lungworm Angiostrongylus cantonensis . The intermediate hosts of A....
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First instar and adult male bed bugs, Cimex lectularius (Hemiptera: Cimicidae), increase feeding activity in the presence of adult females
BackgroundBed bugs, Cimex lectularius , form day-time aggregations from which they depart at night to feed on human blood. Obtaining an initial blood...
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The origin and insecticide resistance of Aedes albopictus mosquitoes established in southern Mozambique
BackgroundThe Aedes albopictus mosquito is of medical concern due to its ability to transmit viral diseases, such as dengue and chikungunya. Aedes...
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A quantitative modeling framework to understand the physiology of the hypothalamic-pituitary-adrenal axis and interaction with cortisol replacement therapy
Congenital adrenal hyperplasia (CAH) is characterized by impaired adrenal cortisol production. Hydrocortisone (synthetic cortisol) is the...
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Assessment of the influence of levees along Yangtze River on Oncomelania hupensis, the intermediate host of Schistosoma japonicum
BackgroundOncomelania hupensis is the exclusive intermediate host of Schistosoma japonicum in China. Snail control is an essential component of...
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Nicotinamide mitigates visceral leishmaniasis by regulating inflammatory response and enhancing lipid metabolism
BackgroundCurrently, treatment regimens for visceral leishmaniasis (VL) are limited because of the presence of numerous adverse effects....
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Infectivity of Plasmodium parasites to Aedes aegypti and Anopheles stephensi mosquitoes maintained on blood-free meals of SkitoSnack
BackgroundAedes and Anopheles mosquitoes are responsible for tremendous global health burdens from their transmission of pathogens causing malaria,...
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Effects of a blood-free mosquito diet on fitness and gonotrophic cycle parameters of laboratory reared Anopheles gambiae sensu stricto
BackgroundThe current rise of new innovative tools for mosquito control, such as the release of transgenic mosquitoes carrying a dominant lethal gene...
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Likelihood comparisons in bounded outcome score analysis must be internally consistent
Clinical trial endpoints are often bounded outcome scores (BOS), which are variables having restricted values within finite intervals. Common...