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Proactive home-based malaria management in rural communities of Bassar Health District in northern Togo from 2014 to 2017: PECADOM + , a pilot experiment
BackgroundTogo's National Malaria Control Programme has initiated an active home-based malaria management model for all age groups in rural areas of...
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Assessment of the influence of levees along Yangtze River on Oncomelania hupensis, the intermediate host of Schistosoma japonicum
BackgroundOncomelania hupensis is the exclusive intermediate host of Schistosoma japonicum in China. Snail control is an essential component of...
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Human cytomegalovirus microRNAs: strategies for immune evasion and viral latency
Viruses use various strategies and mechanisms to deal with cells and proteins of the immune system that form a barrier against infection. One of...
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Cultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
BackgroundThe Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the...
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Impact of the COVID-19 pandemic on extended-spectrum β-lactamase producing Escherichia coli in urinary tract and blood stream infections: results from a nationwide surveillance network, Finland, 2018 to 2022
BackgroundBefore the COVID-19 pandemic there has been a constant increase in antimicrobial resistance (AMR) of Escherichia coli , the most common...
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GIS-based spatiotemporal map** of malaria prevalence and exploration of environmental inequalities
Malaria poses a significant threat to global health, with particular severity in Nigeria. Understanding key factors influencing health outcomes is...
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A randomised trial of malaria vaccine R21/Matrix-M™ with and without antimalarial drugs in Thai adults
In preparation for mass vaccinations with R21/Matrix-M™ combined with mass administrations of dihydroartemisinin, piperaquine, and a single low dose...
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Development and validation of machine learning models to predict MDRO colonization or infection on ICU admission by using electronic health record data
BackgroundMultidrug-resistant organisms (MDRO) pose a significant threat to public health. Intensive Care Units (ICU), characterized by the extensive...
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Secondary attack rate following on-site isolation of patients with suspected COVID-19 in multiple-bed rooms
The implementation of isolation precautions for patients with suspected Coronavirus Disease 2019 (COVID-19) and pending test results is resource...
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Fecal microbiota transplantation alters gut phage communities in a clinical trial for obesity
BackgroundFecal microbiota transplantation (FMT) is a therapeutic intervention used to treat diseases associated with the gut microbiome. In the...
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Genotypic characterization of novel S-DEL variants of porcine epidemic diarrhea virus identified in South Korea
The highly pathogenic genotype 2b (HP-G2b) of porcine epidemic diarrhea virus (PEDV), which caused a pandemic in 2013–2014, evolved in South Korea...
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Infectivity of Plasmodium parasites to Aedes aegypti and Anopheles stephensi mosquitoes maintained on blood-free meals of SkitoSnack
BackgroundAedes and Anopheles mosquitoes are responsible for tremendous global health burdens from their transmission of pathogens causing malaria,...
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Yixin-Fumai granules modulate autophagy through the PI3K/AKT/FOXO pathway and lead to amelioration of aging mice with sick sinus syndrome
ObjectiveBy employing network pharmacology alongside molecular docking techniques, we can delve into the intricate workings of Yixin-Fumai granules...
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Nicotinamide mitigates visceral leishmaniasis by regulating inflammatory response and enhancing lipid metabolism
BackgroundCurrently, treatment regimens for visceral leishmaniasis (VL) are limited because of the presence of numerous adverse effects....
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Efficacy and safety of chloroquine plus primaquine for the treatment of Plasmodium vivax malaria in Hamusit site, Northwestern Ethiopia
BackgroundPlasmodium vivax malaria is still an important public health problem in Ethiopia. Unlike Plasmodium falciparum, P. vivax has a dormant...
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Effects of a blood-free mosquito diet on fitness and gonotrophic cycle parameters of laboratory reared Anopheles gambiae sensu stricto
BackgroundThe current rise of new innovative tools for mosquito control, such as the release of transgenic mosquitoes carrying a dominant lethal gene...
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Metatranscriptomics-guided genome-scale metabolic reconstruction reveals the carbon flux and trophic interaction in methanogenic communities
BackgroundDespite rapid advances in genomic-resolved metagenomics and remarkable explosion of metagenome-assembled genomes (MAGs), the function of...
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Impact on pregnancy outcomes of intermittent preventive treatment with sulfadoxine-pyrimethamine in urban and peri-urban Papua New Guinea: a retrospective cohort study
BackgroundIntermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) reduces malaria-attributable adverse pregnancy...
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Three novel Enterobacter cloacae bacteriophages for therapeutic use from Ghanaian natural waters
Infections caused by multidrug-resistant (MDR) bacteria are a growing global concern. Enterobacter cloacae complex (ECC) species are particularly...
