Search
Search Results
-
Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice
BackgroundThe transition from childhood to adulthood, or adolescence, a developmental stage, is characterized by psychosocial and biological changes....
-
MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome
BackgroundPolycystic ovary syndrome (PCOS), the most common endocrine disorder in premenopausal women, is associated with increased obesity,...
-
Sex-specific differences in the mechanisms for enhanced thromboxane A2-mediated vasoconstriction in adult offspring exposed to prenatal hypoxia
BackgroundPrenatal hypoxia, a common pregnancy complication, leads to impaired cardiovascular outcomes in the adult offspring. It results in impaired...
-
Sexually dimorphic effects of prenatal alcohol exposure on the murine skeleton
BackgroundPrenatal alcohol exposure (PAE) can result in lifelong disabilities known as foetal alcohol spectrum disorder (FASD) and is associated with...
-
Sex and gender differences in adverse events following influenza and COVID-19 vaccination
IntroductionActive and passive surveillance studies have found that a greater proportion of females report adverse events (AE) following receipt of...
-
Differently different?: A commentary on the emerging social cognitive neuroscience of female autism
Autism is a neurodevelopmental condition, behaviourally identified, which is generally characterised by social communication differences, and...
-
Sexual dimorphism in colorectal cancer: molecular mechanisms and treatment strategies
IntroductionSexual dimorphism significantly influences cancer incidence and prognosis. Notably, females exhibit a lower risk and favorable prognosis...
-
Relationship between sex biases in gene expression and sex biases in autism and Alzheimer’s disease
BackgroundSex differences in the brain may play an important role in sex-differential prevalence of neuropsychiatric conditions.
Methods ...
-
Testosterone deficiency promotes arterial stiffening independent of sex chromosome complement
BackgroundSex hormones and sex chromosomes play a vital role in cardiovascular disease. Testosterone plays a crucial role in men’s health. Lower...
-
Low testosterone levels relate to poorer cognitive function in women in an APOE-ε4-dependant manner
BackgroundPast research suggests that low testosterone levels relate to poorer cognitive function and higher Alzheimer’s disease (AD) risk; however,...
-
CGRP as a potential mediator for the sexually dimorphic responses to traumatic brain injury
BackgroundThe outcomes of traumatic brain injury (TBI) exhibit variance contingent upon biological sex. Although female sex hormones exert...
-
Fatty Liver Index (FLI) is the best score to predict MASLD with 50% lower cut-off value in women than in men
BackgroundMetabolic dysfunction-associated steatotic liver disease (MASLD) is defined by the presence of hepatic steatosis, detected on...
-
Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis
BackgroundDifferences in immune responses between women and men are leading to a strong sex bias in the incidence of autoimmune diseases that...
-
Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders
BackgroundSex differences exist in the prevalence and clinical manifestation of several mental disorders, suggesting that sex-specific brain...
-
Sex-specific impacts of prenatal bisphenol A exposure on genes associated with cortical development, social behaviors, and autism in the offspring’s prefrontal cortex
BackgroundRecent studies have shown that prenatal BPA exposure altered the transcriptome profiles of autism-related genes in the offspring’s...
-
Early adversity causes sex-specific deficits in perforant pathway connectivity and contextual memory in adolescent mice
BackgroundEarly life adversity impairs hippocampal development and function across diverse species. While initial evidence indicated potential...
-
Sex-dependent effects of chronic intermittent hypoxia: implication for obstructive sleep apnea
BackgroundObstructive sleep apnea (OSA) affects 10–26% of adults in the United States with known sex differences in prevalence and severity. OSA is...
-
Whole-brain connections of glutamatergic neurons in the mouse lateral habenula in both sexes
BackgroundThe lateral habenula (LHb) is an epithalamus nucleus that is evolutionarily conserved and involved in various physiological functions, such...
-
Sex differences of post-Covid patients undergoing outpatient pulmonary rehabilitation
BackgroundFollowing years of pandemic severe acute respiratory syndrome coronavirus 2 infections labelled Covid-19, long lasting impairment...
-
Treating sex and gender differences as a continuous variable can improve precision cancer treatments
BackgroundThe significant sex and gender differences that exist in cancer mechanisms, incidence, and survival, have yet to impact clinical practice....
