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  1. No Access

    Article

    The multifunctional adaptor protein HIP-55 couples Smad7 to accelerate TGF-β type I receptor degradation

    Transforming growth factor β (TGF-β) is a multifunctional polypeptide that plays critical roles in regulating a broad range of cellular functions and physiological processes. TGF-β signalling dysfunction contr...

    Yang Sun, Zi-jian Li in Acta Pharmacologica Sinica (2022)

  2. Article

    Open Access

    Membrane nanotubes facilitate the propagation of inflammatory injury in the heart upon overactivation of the β-adrenergic receptor

    Acute sympathetic stress quickly induces cardiac inflammation and injury, suggesting that pathogenic signals rapidly spread among cardiac cells and that cell-to-cell communication may play an important role in...

    **g Shen, Ji-Min Wu, Guo-Min Hu, Ming-Zhe Li, Wen-Wen Cong… in Cell Death & Disease (2020)

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  3. Article

    Open Access

    Mitochondria are transported along microtubules in membrane nanotubes to rescue distressed cardiomyocytes from apoptosis

    Membrane nanotubes (MNTs) act as “highways” between cells to facilitate the transfer of multiple signals and play an important role in many diseases. Our previous work reported on the transfer of mitochondria ...

    **g Shen, Jiang-Hui Zhang, Han **ao, Ji-Min Wu, Kang-Min He… in Cell Death & Disease (2018)

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  4. Article

    Proteome reference map and regulation network of neonatal rat cardiomyocyte

    To study and establish a proteome reference map and regulation network of neonatal rat cardiomyocyte.

    Zi-jian Li, Ning Liu, Qi-de Han, You-yi Zhang in Acta Pharmacologica Sinica (2011)

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