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44,328 Result(s)
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Open AccessCorrection: Schisandrin B Inhibits Osteosarcoma Cell Proliferation and Promotes Apoptosis Through PI3K/AKT/mTOR Pathway Mediated Autophagy
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Open AccessPedigree analysis exploring the inconsistency between diverse phenotypes and testing criteria for germline TP53 mutations in Chinese women with breast cancer
In the present study, we addressed the inconsistency between the testing criteria and diverse phenotypes for germline TP53 mutation in patients with breast cancer in the Chinese population.
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Retraction Note: Mobile client data security storage protocol based on multifactor node evaluation
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Correction to: Knock‑Down of CD24 in Astrocytes Aggravates Oxyhemoglobin‑Induced Hippocampal Neuron Impairment
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Open AccessThe association of SOD and HsCRP with the efficacy of sulforaphane in schizophrenia patients with residual negative symptoms
Emerging evidence indicates a connection between oxidative stress, immune-inflammatory processes, and the negative symptoms of schizophrenia. In addition to possessing potent antioxidant and anti-inflammatory ...
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Article
Open AccessAre children with IgA nephropathy different from adult patients?
Previously, several studies have indicated that pediatric IgA nephropathy (IgAN) might be different from adult IgAN, and treatment strategies might be also different between pediatric IgAN and adult IgAN.
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Open AccessPyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling
Fulminant hepatitis (FH) is a life-threatening clinical liver syndrome characterized by substantial hepatocyte necrosis and severe liver damage. FH is typically associated with severe oxidative stress, inflamm...
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Open AccessFeasible CT features to distinguish incidental rib enhancement from sclerotic metastasis in patients with malignancies
To investigate the CT features of incidental rib enhancement (RE) and to summarize the CT characteristics for distinguishing the RE from sclerotic metastasis (SM) in patients with malignancies.
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Open AccessMiR-425-5p suppression of Crebzf regulates oocyte aging via chromatin modification
Female infertility due to declining oocyte quality with age remains a significant challenge for patients and physicians, despite extensive research efforts. Recent studies suggest that microRNAs (miRNAs), whic...
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Open AccessA new kinematic model for revolute clearance joints with noncircular bushing and pin in planar multibody systems
Due to manufacturing error and wear, the profiles of bushing and pin in revolute clearance joints are usually non-circular, while traditional kinematic models for revolute clearance joints generally assume a c...
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Open AccessRisk factors of prognosis for spontaneous cerebellar hemorrhage: a systematic review and meta-analysis
The most deadly type of spontaneous intracerebral hemorrhage is spontaneous cerebellar hemorrhage (SCH). The purpose of this meta-analysis was to investigate risk factors for prognosis in SCH patients to provi...
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Open AccessAssociations between modifiable risk factors and hepatocellular carcinoma: a trans-ancestry Mendelian randomization study
Potentially modifiable risk factors for hepatocellular carcinoma (HCC) have been investigated in observational epidemiology studies in East Asian and European populations, whereas the causal associations of mo...
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Open AccessDesigning preschool children's educational games for enlightenment through decision analysis methods
As an innovative form of digital online education, educational games have potentially significant impacts on preschool children's enlightenment education. Identifying key factors for effective design is crucia...
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Open AccessStructural iterative rounding for generalized k-median problems
This paper considers approximation algorithms for generalized k-median problems. These problems can be informally described as k-median with a constant number of extra constraints, and includes k-median with outl...
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Open AccessEffectiveness and safety of finerenone in Chinese CKD patients without diabetes: a retrospective, real-world study
Finerenone, a non-steroidal mineralocorticoid receptor antagonist, has previously demonstrated its efficacy and safety in chronic kidney disease (CKD) associated with diabetes mellitus. Given its therapeutic p...
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Open AccessCreation and validation of the first infinium DNA methylation array for the human imprintome
Differentially methylated imprint control regions (ICRs) regulate the monoallelic expression of imprinted genes. Their epigenetic dysregulation by environmental exposures throughout life results in the formati...
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Open AccessA systematic review of the drug-drug interaction between Statins and Quinolones
Statins are widely used in cardiovascular disease (CVD) as a common lipid-lowering drug, while quinolones are widely used for the treatment of infectious diseases. It is common to see CVD in combination with i...
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Open AccessHabitat radiomics and deep learning fusion nomogram to predict EGFR mutation status in stage I non-small cell lung cancer: a multicenter study
Develop a radiomics nomogram that integrates deep learning, radiomics, and clinical variables to predict epidermal growth factor receptor (EGFR) mutation status in patients with stage I non-small cell lung can...
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Open AccessRibonuclease 4 functions as an intestinal antimicrobial protein to maintain gut microbiota and metabolite homeostasis
Antimicrobial proteins contribute to host-microbiota interactions and are associated with inflammatory bowel disease (IBD), but our understanding on antimicrobial protein diversity and functions remains incomp...
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Open AccessAnalysis of barriers associated with emergency medical service activation in patients with acute stroke and acute myocardial infarction from Zhongjiang County of Sichuan Province in China
The purpose of this study was to investigate the preferred modes of transportation to the hospital among patients with acute stroke and acute myocardial infarction (AMI), as well as to identify the factors tha...