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  1. No Access

    Article

    Ion Channel Genes and Epilepsy: Functional Alteration, Pathogenic Potential, and Mechanism of Epilepsy

    Ion channels are crucial in the generation and modulation of excitability in the nervous system and have been implicated in human epilepsy. Forty-one epilepsy-associated ion channel genes and their mutations a...

    Feng Wei, Li-Min Yan, Tao Su, Na He, Zhi-Jian Lin, Jie Wang… in Neuroscience Bulletin (2017)

  2. No Access

    Article

    Sub-region analysis of DMD gene in cases with idiopathic generalized epilepsy

    Gene sub-region encoded protein domain is the basic unit for protein structure and function. The DMD gene is the largest coding gene in humans, with its phenotype relevant to idiopathic generalized epilepsy. We h...

    Zhi-Jian Lin, Bi-**a Huang, Li-Fang Su, Sheng-Yin Zhu, Jun-Wei He… in neurogenetics (2023)

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    Article

    Gene–gene interaction network analysis indicates CNTN2 is a candidate gene for idiopathic generalized epilepsy

    Twin and family studies have established the genetic contribution to idiopathic generalized epilepsy (IGE). The genetic architecture of IGE is generally complex and heterogeneous, and the majority of the genet...

    Zhi-Jian Lin, Jun-Wei He, Sheng-Yin Zhu, Li-Hong Xue, Jian-Feng Zheng… in Neurogenetics (2024)