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  1. Article

    Open Access

    Double-edged roles of ferroptosis in endometriosis and endometriosis-related infertility

    Endometriosis is strongly associated with infertility. Several mechanisms have been reported in an attempt to elucidate the pathophysiological effects that lead to reduced fertility in women with endometriosis...

    Yangshuo Li, Yalun He, Wen Cheng, Zhihao Zhou, Zhexin Ni… in Cell Death Discovery (2023)

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  2. Article

    Open Access

    Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity

    Endometriosis (EMs) occurs in approximately 50% of women with infertility. The main causes of EMs-related infertility are follicle dysplasia and reduced oocyte quality. Iron overload occurs in ovarian follicul...

    Zhexin Ni, Yangshuo Li, Di Song, Jie Ding, Shanshan Mei, Shuai Sun… in Cell Death & Disease (2022)

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  3. No Access

    Article

    Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex

    The molecular chaperone Hsp90 modulates the function of specific cell signaling proteins. Although targeting Hsp90 with the antibiotic inhibitor geldanamycin (GA) may be a promising approach for cancer treatme...

    Wan** Xu, **tong Yuan, Zhexin **ang… in Nature Structural & Molecular Biology (2005)