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Article
Open AccessThe P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection
The mutational landscape of SARS-CoV-2 varies at the dominant viral genome sequence and minor genomic variant population. During the COVID-19 pandemic, an early substitution in the genome was the D614G change ...
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Article
Open AccessTranscriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus
In 2014, Western Africa experienced an unanticipated explosion of Ebola virus infections. What distinguishes fatal from non-fatal outcomes remains largely unknown, yet is key to optimising personalised treatme...