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    Article

    Regio-specific biotransformation of alizarin to alizarin methoxide with enhanced cytotoxicity against proliferative cells

    Alizarin has been reported to have an antigenotoxic activity along with an inhibitory effect on the tumor cell growth of human colon carcinoma cells. Alizarin was biotransformed into an O-methoxide derivative usi...

    Trang Thi Huyen Nguyen, Jang Mi Han in Journal of Industrial Microbiology & Biote… (2020)

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    Metabolic engineering of Agrobacterium sp. ATCC31749 for curdlan production from cellobiose

    Curdlan is a commercial polysaccharide made by fermentation of Agrobacterium sp. Its anticipated expansion to larger volume markets demands improvement in its production efficiency. Metabolic engineering for stra...

    Hyun-Dong Shin, Long Liu, Mi-Kyoung Kim in Journal of Industrial Microbiology & Biote… (2016)

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    Bioconversion of compactin into pravastatin by Streptomyces sp.

    Streptomyces sp. Y-110, isolated from soil, modified compactin to pravastatin, a therapeutic agent for hypercholesterolemia. In a batch culture, the highest production of pravastatin was 340 mg l−1 from 750 mg c...

    Joo-Woong Park, Joo-Kyung Lee, Tae-Jong Kwon, Dong-Hee Yi in Biotechnology Letters (2003)

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    Extracellular production of a glycolipid biosurfactant, mannosylerythritol lipid, from Candida antarctica

    Candida antarctica (sp. SY16) required avegetable oil as the carbon source to produce a biosurfactant, mannosylerythritol lipid (MEL-SY16). Biosurfactant production was 31 g l−1 after 7 days in a batch culture a...

    Hee-Sik Kim, Jong-Woon Jeon, Hong-Won Lee, Yong-Il Park in Biotechnology Letters (2002)

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    Article

    Expression of sfp gene and hydrocarbon degradation by Bacillus subtilis

    Bacillus subtilis C9 produces a lipopeptide-type biosurfactant, surfactin, and rapidly degrades alkanes up to a chain length of C19. The nucleotide sequence of the sfp gene cloned from B. subtilis C9 was determi...

    Hee-Sik Kim, Seong-Bin Kim, Seung-Hwan Park, Hee-Mock Oh in Biotechnology Letters (2000)