14 Result(s)
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Article
Yong ** Bae
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessVerification of rebuild-up effect on superficial cardiac lesion of ventricular tachycardia using 3-D printed phantom in volumetric-modulated arc therapy planning
The aim of the study was to evaluate dose distributions on the superficial cardiac lesion surrounded by low-density lungs. Volumetric modulated arc therapy (VMAT) technique was applied to optimize the dose dis...
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Open AccessDysregulation of TFH-B-TRM lymphocyte cooperation is associated with unfavorable anti-PD-1 responses in EGFR-mutant lung cancer
Patients with non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations exhibit an unfavorable response to PD-1 inhibitor through unclear mechanisms. Hypothesizing that EGFR mutati...
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Open AccessParvalbumin-, substance P- and calcitonin gene-related peptide-immunopositive axons in the human dental pulp differ in their distribution of varicosities
Information on the frequency and spatial distribution of axonal varicosities associated with release of neurotransmitters in the dental pulp is important to help elucidate the peripheral mechanisms of dental p...
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Open AccessWnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord
Ependymal cells (ECs) are multiciliated neuroepithelial cells that line the ventricles of the brain and the central canal of the spinal cord (SC). How ependymal motile cilia are maintained remains largely unex...
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Open AccessEffects of image distortion and Hounsfield unit variations on radiation treatment plans: An extended field-of-view reconstruction in a large bore CT scanner
This study aimed to evaluate the effect of image distortion and Hounsfield unit (HU) variation due to the extended field-of-view (eFOV) of the large-bore (LB) computed tomography (CT) on dose distribution. Bot...
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Open AccessNon-invasive coronary physiology based on computational analysis of intracoronary transluminal attenuation gradient
Invasive procedure is a prerequisite for studying coronary physiology. We established the measurement of non-invasive physiological parameters including coronary blood flow (CBF), flow velocity, and microvascu...
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Open AccessA role for the purinergic receptor P2X3 in astrocytes in the mechanism of craniofacial neuropathic pain
The purinergic receptor P2X3, expressed in the central terminals of primary nociceptive neurons in the brainstem, plays an important role in pathological pain. However, little is known about expression of P2X3 in...
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Open AccessA Novel Inhibitor IDPP Interferes with Entry and Egress of HCV by Targeting Glycoprotein E1 in a Genotype-Specific Manner
Despite recent advances in curing chronic hepatitis C (CHC), the high economic burden to therapy, viral drug resistance, difficult to treat hepatitis C virus (HCV) genotypes and patient groups are still of con...
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Open AccessA role of CB1R in inducing θ-rhythm coordination between the gustatory and gastrointestinal insula
Anandamide (AEA) and N-oleoylethanolamine (OEA) are produced in the intestine and brain during fasting and satiety, respectively. Subsequently, AEA facilitates food intake via activation of cannabinoid type-1 rec...
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Open AccessSALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion
Synaptic adhesion molecules regulate various aspects of synapse development, function and plasticity. These functions mainly involve trans-synaptic interactions and positive regulations, whereas cis-interactions ...
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Open AccessInterferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A
Hepatitis C virus (HCV) utilizes autophagy to promote its propagation. Here we show the autophagy-mediated suppression of HCV replication via the endoplasmic reticulum (ER) protein SCOTIN. SCOTIN overexpressio...
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Open AccessThe recent ancestry of Middle East respiratory syndrome coronavirus in Korea has been shaped by recombination
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe cases of human respiratory disease. Since 2012, the victims have mainly come from the Middle East countries or sporadically from some other...
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Open AccessMatrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening
Arterial stiffening is a hallmark of aging and risk factor for cardiovascular disease, yet its regulation is poorly understood. Here we use mouse modeling to show that matrix metalloproteinase-12 (MMP12), a po...
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Open AccessEndoplasmic reticulum stress impairment in the spinal dorsal horn of a neuropathic pain model
Endoplasmic reticulum (ER) stress has been implicated in neurodegenerative diseases, but its role in neuropathic pain remains unclear. In this study, we examined the ER stress and the unfolded protein response...
