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  1. No Access

    Article

    Doxorubicin eluting beads—2: methods for evaluating drug elution and in-vitro:in-vivo correlation

    DC Bead™ is a sulfonate-modified, PVA-based microspherical embolisation agent approved for the treatment of hypervascular tumours and arterio-venous malformations. The beads have previously been shown to activ...

    M. Victoria Gonzalez, Yiqing Tang in Journal of Materials Science: Materials in… (2008)

  2. Article

    Open Access

    Comparison of DC Bead-irinotecan and DC Bead-topotecan drug eluting beads for use in locoregional drug delivery to treat pancreatic cancer

    DC Bead® is a drug delivery embolisation system that can be loaded with doxorubicin or irinotecan for the treatment of a variety of liver cancers. In this study we demonstrate that the topoisomerase I inhibitor t...

    Richard E. J. Forster, Sharon A. Small in Journal of Materials Science: Materials in… (2010)

  3. No Access

    Article

    Synthesis and characterization of image-able polyvinyl alcohol microspheres for image-guided chemoembolization

    Therapeutic embolization of blood vessels is a minimally invasive, catheter-based procedure performed with solid or liquid emboli to treat bleeding, vascular malformations, and vascular tumors. Hepatocellular ...

    Ayele H. Negussie, Matthew R. Dreher in Journal of Materials Science: Materials in… (2015)

  4. Article

    Open Access

    DC BeadM1™: towards an optimal transcatheter hepatic tumour therapy

    Clinical use of DC Bead™ loaded with doxorubicin (DEBDOX™) or irinotecan (DEBIRI™), for the treatment of primary and secondary tumours of the liver respectively, is showing great promise. Recently there has be...

    Andrew L. Lewis, Matthew R. Dreher in Journal of Materials Science: Materials in… (2015)