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Article

Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding

Insufficient insulin secretion is a hallmark of type 2 diabetes and has been attributed to beta cell identity loss characterized by decreased expression of several key beta cell genes. The pro-inflammatory fac...

Adriana Ibarra Urizar, Michala Prause, Lars Roed Ingerslev… in Cell Death & Disease (2023)