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Article
Interactions of the HSV-1 UL25 capsid protein with cellular microtubule-associated protein
An interaction between the HSV-1 UL25 capsid protein and cellular microtubule-associated protein was found using a yeast two-hybrid screen and β-D-galactosidase activity assays. Immunofluorescence microscopy o...
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Article
Open AccessGenomic diversity of citrate fermentation in Klebsiella pneumoniae
It has long been recognized that Klebsiella pneumoniae can grow anaerobically on citrate. Genes responsible for citrate fermentation of K. pneumoniae were known to be located in a 13-kb gene cluster on the chromo...
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Article
Host cell protein C9orf69 promotes viral proliferation via interaction with HSV-1 UL25 protein
In light of the scarcity of reports on the interaction between HSV-1 nucleocapsid protein UL25 and its host cell proteins, the purpose of this study is to use yeast two-hybrid screening to search for cellular ...
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Article
Open AccessGenoty** analysis of Helicobacter pylori using multiple-locus variable-number tandem-repeats analysis in five regions of China and Japan
H. pylori (Helicobacter pylori) is the major causative agent of chronic active gastritis. The population of H. pylori shows a high genomic variability among isolates. And the polymorphism of repeat-units of genom...
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Article
Open AccessFunctional characterization and proteomic analysis of lolA in Xanthomonas campestris pv. campestris
The gram-negative Xanthomonas campestris pv. campestris is the pathogenic bacterium that causes black rot disease in crucifers. The virulence determinants of this bacterium include extracellular enzymes, exopolys...
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Article
Open AccessCharacterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery
The capability of gut microbiota in degrading foods and drugs administered orally can result in diversified efficacies and toxicity interpersonally and cause significant impact on human health. Production of a...
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Article
Open AccessUpregulation of DUSP6 impairs infectious bronchitis virus replication by negatively regulating ERK pathway and promoting apoptosis
Elucidating virus-cell interactions is fundamental to understanding viral replication and identifying targets for therapeutic control of viral infection. The extracellular signal-regulated kinase (ERK) pathway...
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Article
Open AccessThe lolB gene in Xanthomonas campestris pv. campestris is required for bacterial attachment, stress tolerance, and virulence
Xanthomonas campestris pv. campestris (Xcc) is a Gram-negative bacterium that can cause black rot disease in crucifers. The lipoprotein outer membrane localization (Lol) system is involved in the lipoprotein sort...
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Article
Open AccessImmunogenicity and protection of a Pasteurella multocida strain with a truncated lipopolysaccharide outer core in ducks
Pasteurella multocida infection frequently causes fowl cholera outbreaks, leading to huge economic losses to the poultry industry worldwide. This study developed a novel live attenuated P. multocida vaccine strai...
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Article
Brain glucose induces tolerance of Cryptococcus neoformans to amphotericin B during meningitis
Antibiotic tolerance is the ability of a susceptible population to survive high doses of cidal drugs and has been shown to compromise therapeutic outcomes in bacterial infections. In comparison, whether fungic...