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  1. Article

    Open Access

    N1-Methyladenosine modification of mRNA regulates neuronal gene expression and oxygen glucose deprivation/reoxygenation induction

    N1-Methyladenosine (m1A) is an abundant modification of transcripts, plays important roles in regulating mRNA structure and translation efficiency, and is dynamically regulated under stress. However, the charact....

    Zhangyang Qi, Chi Zhang, Huan Jian, Mengfan Hou, Yongfu Lou… in Cell Death Discovery (2023)

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  2. No Access

    Article

    ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2

    Non-alcoholic fatty liver disease (NAFLD) has become a growing public health problem. However, the complicated pathogenesis of NAFLD contributes to the deficiency of effective clinical treatment. Here, we demo...

    Hui-Jun Cao, Hao Jiang, Kai Ding, **ao-Song Qiu, Ning Ma… in Cell Death & Differentiation (2023)

  3. Article

    Open Access

    Plant-frugivore network simplification under habitat fragmentation leaves a small core of interacting generalists

    Habitat fragmentation impacts seed dispersal processes that are important in maintaining biodiversity and ecosystem functioning. However, it is still unclear how habitat fragmentation affects frugivorous inter...

    Wande Li, Chen Zhu, Ingo Grass, Diego P. Vázquez, Duorun Wang… in Communications Biology (2022)

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  4. No Access

    Article

    Grazing Offsets Nitrogen Enrichment Effects on Species Richness by Promoting the Random Colonization of Local Species in an Alpine Grassland

    Nitrogen (N)-induced declines in species richness can be offset by grazing via the suppression of dominant species to increase ground-level light. However, it is not known whether grazing-mediated locally colo...

    Ming-Hua Song, ** Chen, **ng-Liang Xu, Yi-Kang Li, Jun-Qin Gao, Hua OuYang in Ecosystems (2020)

  5. Article

    Open Access

    Structures of β-glycosidase LXYL-P1-2 reveals the product binding state of GH3 family and a specific pocket for Taxol recognition

    LXYL-P1-2 is one of the few xylosidases that efficiently catalyze the reaction from 7-β-xylosyl-10-deacetyltaxol (XDT) to 10-deacetyltaxol (DT), and is a potential enzyme used in Taxol industrial production. H...

    Lin Yang, Tian-Jiao Chen, Fen Wang, Li Li, Wen-Bo Yu, Yi-Kang Si… in Communications Biology (2020)

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  6. No Access

    Article

    Pro-Angiogenic Actions of CMC-Derived Extracellular Vesicles Rely on Selective Packaging of Angiopoietin 1 and 2, but Not FGF-2 and VEGF

    While the fundamental mechanism by which cardiac cell therapy mitigates ventricular dysfunction in the post ischemic heart remains poorly defined, donor cell paracrine signaling is presumed to be a chief contr...

    Marcin Wysoczynski, Asif Pathan, Joseph B. Moore IV… in Stem Cell Reviews and Reports (2019)

  7. No Access

    Article

    SynCAM, a novel putative tumor suppressor, suppresses growth and invasiveness of glioblastoma

    SynCAM, also named by TSLC1, SgIGSF and IGSF4, was identified as a neural tissue-specific immunoglobulin-like cell–cell adhesion molecule. However, the role of SynCAM in tumorigenesis remains elusive. We aimed...

    **aoju Zhang, Wei Li, Yi Kang, Jianguo Zhang, Huijuan Yuan in Molecular Biology Reports (2013)

  8. No Access

    Article

    Effects of Taurine–Magnesium Coordination Compound on Ionic Channels in Rat Ventricular Myocytes of Arrhythmia Induced by Ouabain

    Taurine–magnesium coordination compound (TMCC) has anti-arrhythmic effects. The aim of the present study was to explore the targets of the anti-arrhythmic effect of TMCC and the electrophysiological effects of...

    Lin Zhao, Jianshi Lou, Hong Wu, Yongqiang Yin, Yi Kang in Biological Trace Element Research (2012)

  9. No Access

    Article

    Inhibition of Sodium Current by Taurine Magnesium Coordination Compound Prevents Cesium Chloride-Induced Arrhythmias

    The mechanism(s) by which taurine magnesium coordination compound (TMCC) inhibits experimental arrhythmias remains poorly understood. The purpose of this study was to observe the effects of TMCC against cesium...

    Yongqiang Yin, Ke Wen, Yanna Wu, Yi Kang, Jianshi Lou in Biological Trace Element Research (2012)

  10. No Access

    Article

    Berberine inhibits HEp-2 cell invasion induced by Chlamydophila pneumoniae infection

    This study investigated the inhibitory effects of berberine on Chlamydophila (Chlamydia) pneumoniae infection-induced HEp-2 cell invasion and explored the possible mechanisms involved in this process. C. pneumoni...

    Li Jun Zhang, Li Jun Zhang, Wei Quan, Bei Bei Wang… in The Journal of Microbiology (2011)