17 Result(s)
within
Article
Yi-Kang **ng
Biomedicine
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Article
Open AccessAdipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer
Ovarian carcinoma (OC) is a fatal malignancy, with most patients experiencing recurrence and resistance to chemotherapy. In contrast to hematogenous metastasizing tumors, ovarian cancer cells disseminate withi...
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Open AccessMolecular phylogeny of the family Rhabdiasidae (Nematoda: Rhabditida), with morphology, genetic characterization and mitochondrial genomes of Rhabdias kafunata and R. bufonis
The family Rhabdiasidae (Nematoda: Rhabditida) is a globally distributed group of nematode parasites, with over 110 species parasitic mainly in amphibians and reptiles. However, the systematic position of the ...
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Categorizing objects from MEG signals using EEGNet
Magnetoencephalography (MEG) signals have demonstrated their practical application to reading human minds. Current neural decoding studies have made great progress to build subject-wise decoding models to extr...
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Open AccessCorrection to: Silenced lncRNA DDX11-AS1 or up-regulated microRNA-34a-3p inhibits malignant phenotypes of hepatocellular carcinoma cells via suppression of TRAF5
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Open AccessSilenced lncRNA DDX11-AS1 or up-regulated microRNA-34a-3p inhibits malignant phenotypes of hepatocellular carcinoma cells via suppression of TRAF5
Studies have discussed long noncoding RNA DDX11-AS1 (DDX11-AS1)-mediated downstream mechanism in hepatocellular carcinoma (HCC). The goal of this study was to investigate the regulatory mechanism of DDX11-AS1-...
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Blockade of Endogenous Angiotensin-(1–7) in Hypothalamic Paraventricular Nucleus Attenuates High Salt-Induced Sympathoexcitation and Hypertension
Angiotensin (Ang)-(1–7) is an important biologically-active peptide of the renin-angiotensin system. This study was designed to determine whether inhibition of Ang-(1–7) in the hypothalamic paraventricular nuc...
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Chronic Intracerebroventricular Infusion of Metformin Inhibits Salt-Sensitive Hypertension via Attenuation of Oxidative Stress and Neurohormonal Excitation in Rat Paraventricular Nucleus
Metformin (MET), an antidiabetic agent, also has antioxidative effects in metabolic-related hypertension. This study was designed to determine whether MET has anti-hypertensive effects in salt-sensitive hypert...
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Therapeutic effects of a taurine-magnesium coordination compound on experimental models of type 2 short QT syndrome
Short QT syndrome (SQTS) is a genetic arrhythmogenic disease that can cause malignant arrhythmia and sudden cardiac death. The current therapies for SQTS have application restrictions. We previously found that...
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Article
Generation of regulatory dendritic cells after treatment with paeoniflorin
Regulatory dendritic cells are a potential therapeutic tool for assessing a variety of immune overreaction diseases. Paeoniflorin, a bioactive glucoside extracted from the Chinese herb white paeony root, has b...
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Article
EGFR mediates docetaxel resistance in human castration-resistant prostate cancer through the Akt-dependent expression of ABCB1 (MDR1)
Recent studies have shown that docetaxel-based chemotherapy confers a survival benefit in patients with castration-resistant prostate cancer (PC). Also epidermal growth factor receptor (EGFR) was found to ha...
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Open AccessComparison of warfarin therapy clinical outcomes following implementation of an automated mobile phone-based critical laboratory value text alert system
Computerized alert and reminder systems have been widely accepted and applied to various patient care settings, with increasing numbers of clinical laboratories communicating critical laboratory test values to...
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Open AccessDown-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications
Metastatic renal cell carcinoma (RCC) is highly resistant to systemic chemotherapy. Unfortunately, nearly all patients die of the metastatic and chemoresistant RCC. Recent studies have shown the atypical PKCζ ...
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Open AccessWhole-genome sequence of Schistosoma haematobium
Robin Gasser and his colleagues report the whole-genome sequence of Schistosoma haematobium. They include comparisons to the genome sequences of S. mansoni and S. japonicum, the two other species that cause schis...
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α-Glucosidase inhibitory and antioxidant properties and antidiabetic activity of Hypericum ascyron L.
Different solvent extracts of Hypericum ascyron L. were evaluated by α-glucosidase inhibitory activity and DPPH, ABTS and FRAP assays, respectively, for antioxidant properties in vitro. EtOAC and MeOH extracts sh...
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Antioxidant phenolic compounds and flavonoids of Mitragyna rotundifolia (Roxb.) Kuntze in vitro
Different solvent extracts of leaves and bark of Mitragyna rotundifolia (Roxb.) Kuntze were evaluated by DPPH, ABTS, and FRAP assays, respectively, for antioxidant properties. Total phenolic and flavonoid content...
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Open AccessCharacterization of membranous and cytoplasmic EGFR expression in human normal renal cortex and renal cell carcinoma
Metastatic renal cell carcinoma (RCC) is highly resistant to conventional systemic treatments, including chemotherapy, radiotherapy and hormonal therapies. Previous studies have shown over-expression of EGFR i...
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Prevalence of TT Virus and GBV-C Infections among Patients with Liver Diseases and the General Population in Shanghai, China
To determine the prevalence of TT virus (TTV) and GB virus C/hepatitis G virus (GBV-C) infections among patients with liver disease and the general population in Shanghai, China, we studied 90 patients with li...
