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  1. Article

    Identification of serum metabolites enhancing inflammatory responses in COVID-19

    Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is characterized by a strong production of inflammatory cytokines such as TNF and IL-6, which underl...

    Chen-Song Zhang, Bingchang Zhang, Mengqi Li, **aoyan Wei in Science China Life Sciences (2022)

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    AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1

    The sympathetic nervous system–catecholamine–uncoupling protein 1 (UCP1) axis plays an essential role in non-shivering adaptive thermogenesis. However, whether there exists a direct effector that physically co...

    Meng Shi, **ao-Yu Huang, **n-Yi Ren, **ao-Yan Wei, Yue Ma in Nature Cell Biology (2021)

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    CELSR1 is a positive regulator of endothelial cell migration and angiogenesis

    Cadherin is an epidermal growth factor and laminin-G seven-pass G-type receptor 1 (CELSR1) is a key component of the noncanonical Wnt/planar cell polarity (PCP) pathway that critically regulates endothelial ce...

    Yi-Hong Zhan, Qi-Cong Luo, **ao-Rong Zhang, Nai-An **ao in Biochemistry (Moscow) (2016)