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Article
GDF11 promotes wound healing in diabetic mice via stimulating HIF-1ɑ-VEGF/SDF-1ɑ-mediated endothelial progenitor cell mobilization and neovascularization
Non-healing diabetic wounds (DW) are a serious clinical problem that remained poorly understood. We recently found that topical application of growth differentiation factor 11 (GDF11) accelerated skin wound he...
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Article
Open AccessThe effects of BMMSC treatment on lung tissue degeneration in elderly macaques
Age-associated lung tissue degeneration is a risk factor for lung injury and exacerbated lung disease. It is also the main risk factor for chronic lung diseases (such as COPD, idiopathic pulmonary fibrosis, ca...
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Article
Open AccessThe transcriptional profiles and functional implications of long non-coding RNAs in the unfolded protein response
The unfolded protein response (UPR) is activated, when the folding capacity is compromised in the endoplasmic reticulum (ER). To date, most studies focused on the coding genes and microRNAs in UPR. Other non-c...
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Article
Role of ZIC1 methylation in hepatocellular carcinoma and its clinical significance
Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies in humans, and its prognosis is generally poor even after surgery. The zinc finger of the cerebellum (ZIC1) gene is a novel tumor suppr...
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Article
Ubiquitin-specific protease 22: a novel molecular biomarker in cervical cancer prognosis and therapeutics
Ubiquitin-specific protease 22 (USP22) exhibits an important function in tumor progression and oncogenesis. The aim of this study was to investigate the role of USP22 and the association with its potential tar...
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Article
Investigation of scale effect for the computation of turbulent flow around a circular cylinder
In order to investigate the scale effect of turbulent flow around a circular cylinder, two similarity numbers (criteria) based on turbulent kinetic and dissipation rates associated with the fluctuation charact...
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Article
The variation of CD4+CD25+ regulatory T cells in the periphery blood and tumor microenvironment of non-small cell lung cancer patients and the downregulation effects induced by CpG ODN
The aim of the study was to observe the variation of CD4+CD25+ regulatory T cells in periphery blood and tumor microenvironment of non-small cell lung cancer (NSCLC) patients and the effects of CpG ODN. The propo...
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Article
An essential solution of water entry problems and its engineering applications
For solving water entry problems, a numerical method is presented, which is a CFD method based on free surface capturing method and Cartesian cut cell mesh. In this approach, incompressible Euler equations for...
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Article
Study of capacitive properties for LT-Li4Mn5O12 in hybrid supercapacitor
Spinel Li4Mn5O12 nanoparticles have been prepared by a very simple sol–gel method. Various initial conditions were studied in order to find the optimal conditions for the synthesis of pure Li4Mn5O12. X-ray diffra...
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Article
Effects of additives and surface treatment on electrochemical performance for bafeo4 electrode
BaFeO4 was prepared by using the raw material K2FeO4. The structure of the product was characterized by X-ray diffraction and infrared radiation. Particle size and morphology were analyzed by SEM. BaFeO4, the mix...
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Article
Discussion on the parameters of design waves
In order to respond the discredit on the design wave standard and to recommend new consideration on design wave parameters, based on the long-term distribution of statistic characteristics of waves and the sho...
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Article
A new composite material Li4Ti5O12–SnO2 for lithium-ion batteries
A new Li4Ti5O12–SnO2 composite anode material for lithium-ion batteries has been prepared by loading SnO2 on Li4Ti5O12 to obtain composite material with improved electrochemical performance relative to Li4Ti5O12 ...
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Article
Mathematical simulation of steep waves at a focus point
Mathematical models simulating steep waves at a focus point are presented in this paper. Simulations of extreme waves in a model basin were used to determine the loads on floating structures induced by the wav...
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Article
Water Quality Modeling and Pollution Control for the Eastern Route of South to North Water Transfer Project in China
South to North Water Transfer Project in China is the largest project over centuries to solve the water shortage problem in vast areas of northern China. It comprises of three routes: the eastern, central and ...
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Article
Commuting Involutions with Fixed Point Set of Variable Codimension
Special generators of the unoriented cobordism ring MO * are constructed to determine some groups $$ J^{{l_{1} ,l_{2}...