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    Article

    Targeting HIF-1α/NOTCH1 pathway eliminates CD44+ cancer stem-like cell phenotypes, malignancy, and resistance to therapy in head and neck squamous cell carcinoma

    Poor prognosis of head and neck squamous cell carcinomas (HNSCCs) results from resistance to chemotherapy and radiotherapy. To uncover the drivers of HNSCC resistance, including stemness and hypoxia, in this s...

    Joo-Yun Byun, Kun Huang, Jong Suk Lee, Wenjie Huang, Li Hu, Xuyu Zheng in Oncogene (2022)

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    Article

    Mass Spectrometry-Based Proteomics Analysis Unveils PTPRS Inhibits Proliferation and Inflammatory Response of Keratinocytes in Psoriasis

    In this study, we used data-independent acquisition-mass spectrometry (DIA-MS) to analyze the serum proteome in psoriasis vulgaris (PsO). The serum proteomes of seven healthy controls and eight patients with P...

    Xuyu Zheng, Cui Zhou, Yulian Hu, Shihao Xu, Li Hu, Biyu Li, **aoqin Zhao in Inflammation (2024)