914 Result(s)
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Article
Open AccessAre children with IgA nephropathy different from adult patients?
Previously, several studies have indicated that pediatric IgA nephropathy (IgAN) might be different from adult IgAN, and treatment strategies might be also different between pediatric IgAN and adult IgAN.
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Research on the Gait Phase Analysis Method of Femoral Amputation Patients Based on the Thin Film Pressure Sensor
The running-in of amputees and prostheses usually requires a long time. Many objective evaluation parameters must be obtained to fit prosthetic orthoses on the amputees. Hence, in this paper, a method for anal...
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Open AccessWater quality management could halve future water scarcity cost-effectively in the Pearl River Basin
Reducing water scarcity requires both mitigation of the increasing water pollution and adaptation to the changing availability and demand of water resources under global change. However, state-of-the-art water...
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Open AccessPrenatal LPS leads to increases in RAS expression within the PVN and overactivation of sympathetic outflow in offspring rats
The renin-angiotensin system (RAS) and the sympathetic nervous system (SNS) are two major blood pressure-regulating systems. The link between the renal and cerebral RAS axes was provided by reflex activation o...
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Rational-designed high-performance anode materials for sodium-ion batteries: a review
Sodium-ion batteries (SIBs) have aroused wide attention because a large amount of sodium reserves has been proven to exist, acquiring less cost compared to lithium-ion batteries (LIBs). Besides, their chemical...
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Open AccessInnovative BIM technology application in the construction management of highway
Within the global architecture, engineering, and construction industry, the use of Building Information Modeling (BIM) technology has significantly expanded. However, given the unique characteristics of road i...
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Follicular Helper T Cells and Follicular Regulatory T Cells Involved in Immune Disorders of Idiopathic Membranous Nephropathy
To investigate the role of follicular helper T (Tfh) cells and follicular regulatory T (Tfr) cells in immune disorders of idiopathic membranous nephropathy (IMN).
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Construction of short synthetic promoters for optimization of ovalbumin expression level in Saccharomyces cerevisiae
Saccharomyces cerevisiae, a common eukaryotic model microorganism that is generally recognized as safe, is widely employed for the heterologous expression of edible and therapeutic proteins. Promoters are crucial...
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Construction of a plasmid-free Escherichia coli strain for lacto-N-neotetraose biosynthesis
Lacto-N-neotetraose (LNnT), with promising bioactive properties, is one of the most significant nonfucosylated human milk saccharides. Recently, its synthesis by microbial fermentation has attracted great attenti...
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Article
Effects of spike-time-dependent plasticity on stochastic resonance in excitatory-inhibitory neuronal networks
The phenomenon in which the response of a neuronal network to a weak signal is significantly enhanced in moderate noise is known as stochastic resonance (SR). Most of the previous studies on the transmission o...
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Simulation and prediction of the dynamic evolution characteristics of resource- and technology-driven economic development models: a case study of the Yangtze River economic belt in China
Resource-driven models and technology-driven models appear in different stages of economic development. In the early stage of industrialization, resource-driven economic development is usually the main develop...
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Association between activity of daily living and depressive symptoms among older adults in China: evidence from the CHARLS
Little is known about the association between activity of daily living (ADL) and depressive symptoms, especially whether there is an interaction between ADL domains, demographic characteristics, and depressive...
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Open AccessIntegration of molecular docking and molecular dynamics simulations with subtractive proteomics approach to identify the novel drug targets and their inhibitors in Streptococcus gallolyticus
Streptococcus gallolyticus (Sg) is a non-motile, gram-positive bacterium that causes infective endocarditis (inflammation of the heart lining). Because Sg has gained resistance to existing antibiotics and there i...
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Comparing collagenase and silver sulfadiazine in deep second-degree burn treatment
The indications for collagenase ointment (CO) and its efficacy are not clearly established in the treatment of second-degree burn wounds. To evaluate the efficacy of CO versus silver sulfadiazine ointment (SSD...
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Sleep patterns, genetic susceptibility, and risk of cirrhosis among individuals with nonalcoholic fatty liver disease
The associations between sleep patterns or behaviors and the risk of cirrhosis and the influence of genetic susceptibility on these associations among NAFLD participants remain inadequately elucidated.
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Open AccessHigher-order topological transport protected by boundary Chern number in phononic crystals
Topological pumps enable robust transports of topological states when the system parameters are varied in a cyclic process. The reported topological pumps are protected by the bulk topology. However, the explo...
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Article
Role and recent progress of P2Y12 receptor in cancer development
P2Y12 receptor (P2Y12R) is an adenosine-activated G protein-coupled receptor (GPCR) that plays a central role in platelet function, hemostasis, and thrombosis. P2Y12R activation can promote platelet aggregatio...
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Open AccessA novel ACE inhibitory peptide from Pelodiscus sinensis Wiegmann meat water-soluble protein hydrolysate
Pelodiscus sinensis meat is a nutritional food and tonic with angiotensin-converting enzyme (ACE) inhibitory activities. To identify the bioactive substances responsible, several bioinformatics methods were integ...
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A single-cell transcriptome atlas of human euploid and aneuploid blastocysts
Aneuploidy is frequently detected in early human embryos as a major cause of early pregnancy failure. However, how aneuploidy affects cellular function remains elusive. Here, we profiled the transcriptomes of ...
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DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis
Post-stroke emotional disorders such as post-stroke anxiety and post-stroke depression are typical symptoms in patients with stroke. They are closely associated with poor prognosis and low quality of life. The...