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    Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers

    G-quadruplexes (G4s) are DNA or RNA structures formed by guanine-rich repeating sequences. Recently, G4s have become a highly attractive therapeutic target for BRCA-deficient cancers. Here, we show that a subs...

    Meng-Zhu Li, Tao Meng, Shan-Shan Song, Xu-Bin Bao, Lan-** Ma in Investigational New Drugs (2021)