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Article
Open AccessMissing genes in the annotation of prokaryotic genomes
Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports that prokaryotic gene finder programs hav...
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Article
Open AccessMulti-dimensional characterization of electrostatic surface potential computation on graphics processors
Calculating the electrostatic surface potential (ESP) of a biomolecule is critical towards understanding biomolecular function. Because of its quadratic computational complexity (as a function of the number of at...
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Article
Open AccessmuBLASTP: database-indexed protein sequence search on multicore CPUs
The Basic Local Alignment Search Tool (BLAST) is a fundamental program in the life sciences that searches databases for sequences that are most similar to a query sequence. Currently, the BLAST algorithm utili...