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  1. Article

    Open Access

    Minimally invasive video-assisted thyroidectomy for the early-stage differential thyroid carcinoma

    Minimally invasive video-assisted thyroidectomy (MIVAT), the modified Miccoli’s thyroid surgery, is the most widespread minimally invasive technique and has been widely used for treatment of thyroid disease. T...

    Jian-jun Yu, Shan-lin Bao, Sheng-lin Yu, Da-Qing Zhang in Journal of Translational Medicine (2012)

  2. Article

    Open Access

    Overexpression of epithelial growth factor receptor (EGFR) predicts better response to neo-adjuvant chemotherapy in patients with triple-negative breast cancer

    Triple negative breast cancer (TNBC) occurs in approximately 10% to 25% of all patients with breast cancer and is associated with poor prognosis. Neo-adjuvant chemotherapy has been reported to produce a higher...

    Yiqing Tang, Li Zhu, Yafen Li, Jun Ji, Jianfang Li in Journal of Translational Medicine (2012)

  3. Article

    Open Access

    Relationship of CD44+CD24-/low breast cancer stem cells and axillary lymph node metastasis

    Axillary node staging plays an important role in the prognostic evaluation and planning of adjuvant treatment. Breast cancer stem cells, identified on the basis of CD44+CD24-/low expression, are associated with m...

    Wei Wei, Hui Hu, Haosheng Tan, Louis WC Chow in Journal of Translational Medicine (2012)

  4. Article

    Open Access

    Decreased expression of C-erbB-2 and CXCR4 in breast cancer after primary chemotherapy

    Biological molecular markers such as proto-oncogene erbB-2 (HER-2/neu, c-erbB-2), the CXC chemokine receptor 4 (CXCR4), estrogen receptor (ER), Proliferating Cell Nuclear Antigen (PCNA), DNA topoisomerase II (top...

    Shi-**n Yang, Wings TY Loo, Louis WC Chow in Journal of Translational Medicine (2012)

  5. Article

    Open Access

    Emodin affects ERCC1 expression in breast cancer cells

    Multi-drug resistance to chemotherapeutic agents is a major cause of treatment failure in breast cancer. In this study, we investigated the effects of emodin on reversing the multi-drug resistance, examined th...

    Jian-min Fu, Jie Zhou, Jian Shi, Jian-sheng **e in Journal of Translational Medicine (2012)

  6. Article

    Open Access

    Mouse model of plasma cell mastitis

    Plasma cell mastitis is distinct from the common form of mastitis and clinically resembles breast carcinoma. The lesion occurs in non-lactating young women, and the incidence rate is rising. Surgical resection...

    Jian-jun Yu, Shan-lin Bao, Sheng-lin Yu, Da-Qing Zhang in Journal of Translational Medicine (2012)

  7. Article

    Open Access

    Gene polymorphism and protein of human pro- and anti-inflammatory cytokines in Chinese healthy subjects and chronic periodontitis patients

    Periodontal disease is thought to arise from the interaction of various factors, including the susceptibility of the host, the presence of pathogenic organisms, and the absence of beneficial species. The genet...

    Wings TY Loo, Chang-bin Fan, Lan-jun Bai, Yuan Yue in Journal of Translational Medicine (2012)

  8. Article

    Open Access

    Using association rules mining to explore pattern of Chinese medicinal formulae (prescription) in treating and preventing breast cancer recurrence and metastasis

    Chinese herbal medicine is increasingly widely used as a complementary approach for control of breast cancer recurrence and metastasis. In this paper, we examined the implicit prescription patterns behind the ...

    Yanhua He, **ao Zheng, Cindy Sit, Wings TY Loo in Journal of Translational Medicine (2012)

  9. Article

    Open Access

    Application of a nanotechnology antimicrobial spray to prevent lower urinary tract infection: a multicenter urology trial

    Catheter-associated urinary tract infection (CAUTI) is a common nosocomial device-associated infection. It is now recognized that the high infection rates were caused by the formation of biofilm on the surface...

    Wei He, Dongmin Wang, Zhangqun Ye, Weihong Qian in Journal of Translational Medicine (2012)

  10. Article

    Open Access

    Comparing serum levels of cardiac biomarkers in cancer patients receiving chemotherapy and subjects with chronic periodontitis

    Chronic periodontitis (CP) is a chronic inflammation associated with elevations of several inflammatory and cardiac markers. Studies implicated CP as one of the etiologies in coronary heart disease (CHD). Card...

    Wings TY Loo, Yuan Yue, Chang-bin Fan, Lan-jun Bai in Journal of Translational Medicine (2012)

  11. Article

    Open Access

    Clinical application of human β-defensin and CD14 gene polymorphism in evaluating the status of chronic inflammation

    Periodontitis is a common disease that affects the periodontal tissue supporting the teeth. This disease is attributed to multiple risk factors, including diabetes, cigarette smoking, alcohol, pathogenic micro...

    Wings TY Loo, Lan-jun Bai, Chang-bin Fan, Yuan Yue in Journal of Translational Medicine (2012)

  12. Article

    Open Access

    Epigenetic change in e-cardherin and COX-2 to predict chronic periodontitis

    DNA methylation of certain genes frequently occurs in neoplastic cells. Although the cause remains unknown, many genes have been identified with such atypical methylation in neoplastic cells. The hypermethylat...

    Wings TY Loo, Lijian **, Mary NB Cheung, Min Wang in Journal of Translational Medicine (2010)