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  1. No Access

    Article

    Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior

    Microtubules and the plus-end-directed microtubule motor Kinesin I are required for the selective accumulation of oskar mRNA at the posterior cortex of the Drosophila melanogaster oocyte, which is essential to po...

    Byeong-Jik Cha, Laura R. Serbus, Birgit S. Koppetsch… in Nature Cell Biology (2002)

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    Article

    TACCing down the spindle poles

    Centrosomes define the poles of mitotic spindles, but spindles that lack centrosomes mediate meiotic chromosome segregation in females. Recent studies provide new insight into anastral-spindle assembly, and in...

    William E. Theurkauf in Nature Cell Biology (2001)

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    Article

    Centrosomes and the Scrambled protein coordinate microtubule-independent actin reorganization

    In Drosophila syncytial blastoderm embryos, centrosomes specify the position of actin-based interphase caps and mitotic furrows. Mutations in the scrambled locus prevent assembly of mitotic furrows, but do not bl...

    Victoria A. Stevenson, Joseph Kramer, Jesse Kuhn… in Nature Cell Biology (2001)

  4. No Access

    Article

    DNA-replication/DNA-damage-dependent centrosome inactivation in Drosophila embryos

    During early embryogenesis of Drosophila melanogaster, mutations in the DNA-replication checkpoint lead to chromosome-segregation failures. Here we show that these segregation failures are associated with the ass...

    Ody C. M. Sibon, Anju Kelkar, Willy Lemstra, William E. Theurkauf in Nature Cell Biology (2000)