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    Modulation of OPRM1 Alternative Splicing by Morphine and HIV–1 Nef

    Clinically used opioids, such as morphine, activate the mu opioid receptor (MOR) encoded by Opioid Receptor Mu 1 (OPRM1) gene. Examination of the opioid receptor genes showed that the human OPRM1 pre–mRNA unde...

    Martina Donadoni, Wenfei Huang, Shadan S. Yarandi in Journal of Neuroimmune Pharmacology (2022)

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    The Impact of Alcohol-Induced Dysbiosis on Diseases and Disorders of the Central Nervous System

    The human digestive tract contains a diverse and abundant microbiota that is important for health. Excessive alcohol use can disrupt the balance of these microbes (known as dysbiosis), leading to elevated bloo...

    **angqian Liu, Michael Vigorito, Wenfei Huang in Journal of Neuroimmune Pharmacology (2022)

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    Involvement of Interferon Regulatory Factor 7 in Nicotine’s Suppression of Antiviral Immune Responses

    Nicotine, the active ingredient in tobacco smoke, suppresses antiviral responses. Interferon regulatory factors (IRFs) regulate transcription of type I interferons (IFNs) and IFN-stimulated genes (ISGs) in thi...

    Haijun Han, Wenfei Huang, Wenjuan Du, Quan Shen in Journal of Neuroimmune Pharmacology (2019)

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    Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells

    Ethanol (EtOH), the main ingredient in alcoholic beverages, is well known for its behavioral, physiological, and immunosuppressive effects. There is evidence that EtOH acts through protein targets to exert its...

    Sulie L. Chang, Wenfei Huang, **n Mao in Journal of Neuroimmune Pharmacology (2018)