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Article
Catalytic Hydrogenolysis of HMF to DMF over N-doped Molybdenum Carbide Catalyst
The effect of organic precursors on catalysts was studied and the preparation of catalyst and reaction conditions were optimized. A 91% selectivity of 2,5-dimethylfuran (DMF) from the hydrogenolysis of 5-hydro...
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Article
Propane Dehydrogenation Using Platinum Supported on Gallium-Doped Silica
The dehydrogenation of propane over Pt supported on Ga-doped silica was investigated, using various meso- and microporous silica supports. The addition of a small amount of Ga (0.5 wt%) to SBA-15 was enough to...
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Article
Modulation of OPRM1 Alternative Splicing by Morphine and HIV–1 Nef
Clinically used opioids, such as morphine, activate the mu opioid receptor (MOR) encoded by Opioid Receptor Mu 1 (OPRM1) gene. Examination of the opioid receptor genes showed that the human OPRM1 pre–mRNA unde...
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Article
The Impact of Alcohol-Induced Dysbiosis on Diseases and Disorders of the Central Nervous System
The human digestive tract contains a diverse and abundant microbiota that is important for health. Excessive alcohol use can disrupt the balance of these microbes (known as dysbiosis), leading to elevated bloo...
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Article
Involvement of Interferon Regulatory Factor 7 in Nicotine’s Suppression of Antiviral Immune Responses
Nicotine, the active ingredient in tobacco smoke, suppresses antiviral responses. Interferon regulatory factors (IRFs) regulate transcription of type I interferons (IFNs) and IFN-stimulated genes (ISGs) in thi...
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Article
Versatile cell ablation tools and their applications to study loss of cell functions
Targeted cell ablation is a powerful approach for studying the role of specific cell populations in a variety of organotypic functions, including cell differentiation, and organ generation and regeneration. Em...
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Article
Ethanol’s Effects on Transient Receptor Potential Channel Expression in Brain Microvascular Endothelial Cells
Ethanol (EtOH), the main ingredient in alcoholic beverages, is well known for its behavioral, physiological, and immunosuppressive effects. There is evidence that EtOH acts through protein targets to exert its...
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Article
Open AccessEffects of Compositional Tailoring on Drug Delivery Behaviours of Silica Xerogel/Polymer Core-shell Composite Nanoparticles
Conventional core-shell polymer nanoparticles usually exhibit a rapid release rate with their release kinetics mainly adjusted through changing composition of the polymer shells, limiting their applications fo...
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Article
Effects of docosahexaenoic acid on locomotor activity in ethanol-treated HIV-1 transgenic rats
Binge drinking affects the onset and progression of human immunodeficiency virus (HIV)-associated neurological disorders. The HIV-1 transgenic (HIV-1Tg) rat was created with a gag- and pol-deleted HIV-1 viral gen...