2,460 Result(s)
-
Article
The radiation from an electrically small circular wire loop implanted in a dissipative homogeneous spherical medium
Radio-frequency rediation properties of the implanted transmitter were studied. Two models using spheres representing the biological body were studied theoretically; one is for current loop without insulation,...
-
Article
Chronic intracranial pressure monitoring by telemetry: Clinical experience
Intracranial pressure (ICP) monitoring is a critical measure for avoiding severe brain dysfunction or brain death by directing supportive therapy so as to prevent ICP increase severe enough to reduce cerebral ...
-
Article
Histochemical localization of zinc in the feline tapetum
High resolution electron microscopy of ultrathin sections confirms the presence of a membrane surrounding the tapetal rods in the cat. Cats depleted of taurine exhibit disruption and disorganization of this me...
-
Article
Contradictory differential staining results with Coomassie Brilliant Blue and silver carbonate on sister chromatids
Coomassie Brilliant Blue, and silver stain, are used in electrophoretic gels to identify polypeptides. The relative staining intensity has been taken as indicating a quantitative difference between proteins. H...
-
Article
In vitro radiolabeling of galactosyl and N-acetylgalactosaminyl moieties of glycoproteins with carbon-14
The primary alcohol group on the carbon 6 of terminal galactosyl and N-acetylgalactosaminyl moieties of glycoproteins can be oxidized to an aldehyde by treatment with galactose oxidase. By reacting these aldeh...
-
Article
Sequence similarity between part of human retinoblastoma susceptibility gene product and a neurofilament protein subunit
Retinoblastoma, is a highly malignant but readily treatable cancer of the retina, which occurs at an incidence of 1 in 20,000 live births in young children. The retinoblastoma gene that determines susceptibili...
-
Article
Activation of antifreeze proteins from larvae of the beetle Dendroides canadensis
Purified antifreeze proteins (AFPs) from the larvae of the beetle Dendroides canadensis do not produce the high levels of antifreeze activity seen in the hemolymph of overwintering larvae, even when the purified ...
-
Article
Retrospective cohort study of risk-factors for esophageal cancer in Linxian, People's Republic of China
A retrospective cohort study of esophageal (including gastric cardia) cancer was conducted to examine dietary and other potential risk factors in Linxian, a high-risk area in P.R. China. Study subjects were id...
-
Article
In situ hybridization of atrial natriuretic peptide mRNA in the endothelial cells of human umbilical vessels
The localization of mRNA encoding preproatrial natriuretic peptide (ANP) was investigated in cultured human umbilical vein endothelial cells (HUVEC) and tissue preparations of umbilical vein and artery. The te...
-
Article
An experimental technique for estimating regional myocardial segment workIn Vivo
We determined the capabilities and limitations of an experimental approach to measure segment work (force × distance) of myocardial regions in thein vivo beating heart. In 18 open-chest anesthetized dogs, segment...
-
Article
An in vitro cell invasion assay: Determination of cell surface proteolytic activity that degrades extracellular matrix
A correlative morphological and biochemical method is described that facilitates assaying the invasive phenotype of tumor cells in vitro. The method involves a labeled matrix substrata to measure the activity ...
-
Article
Human IgA Monoclonal Antibodies Specific for a Major Ragweed Pollen Antigen
Human hybridoma cell lines secreting IgG specific for the major allergen in the pollen of short ragweed, Amb a I, were established from patients who had been receiving antigen injections for immunotherapy. Recomb...
-
Article
Production, characterization and application of monoclonal antibodies against the organophosphorus nerve agent Vx
Two monoclonal antibodies (Vx-BB8 and Vx-EA11) to the chemical warfare agent Vx were produced and characterized. A competitive inhibition enzyme immunoassay was developed to detect Vx concentrations as low as ...
-
Article
Detection of the organophosphorus nerve agent sarin by a competitive inhibition enzyme immunoassay
Two artificial antigens, N αNε-di(O, O-diisopropyl) phosphoryl l-lysine (DIP)-bovine serum albumin (BSA) conjugate (DIP-BSA) and DIP-KLH (keyhole limpet hemocyanin), were synthesized. Anti...
-
Article
The accuracy of prostate cancer staging in a population-based tumor registry and its impact on the Black-White stage difference (Connecticut, United States)
Stage at diagnosis of prostate cancer is a major determinant of survival. Among Blacks, prostate cancer is diagnosed at a later stage of disease than among Whites. This study examined the accuracy of routine c...
-
Article
Inhibition of cancer cell motility and invasion by interleukin-12
Tumour cell motility and attachment are crucial requirements in the formation of metastatic lesions. These properties are affected by a number of cytokines including hepatocyte growth factor/scatter factor (HG...
-
Article
The establishment of two cell lines from a mouse uterine cervical carcinoma (U14) and their metastatic phenotype changes
This paper studies the heterogeneity of metastatic potential of murine cervical carcinoma (U14). Two cell lines, P11–90 and L10–90, were established from a pulmonary metastatic substrain (U14AP11) and a lymphatic...
-
Article
Characterization of phospholipase A2 activation by plasmin in cultured bovine endothelial cells
Treatment of cultured bovine carotid artery endothelial cells with 0.1 µM human plasmin has been reported to induce a receptor-mediated short burst of arachidonate release, which is a pertussis toxin-sensitive an...
-
Article
Production of premature delivery in pregnant rhesus monkeys by androstenedione infusion
The endocrine mechanisms involved in term and preterm delivery in primates, including pregnant women, are poorly understood. In the term monkey, fetal plasma androgen concentration rises to two hundred times t...
-
Article
Multiplicity of brain cysteine sulfinic acid decarboxylase — Purification, characterization and subunit structure
Cysteine sulfinic acid decarboxylase (CSAD), the rate-limiting enzyme in taurine biosynthesis, appears to be present in the brain in multiple isoforms. Two distinct forms of CSAD, referred to as CSAD I and CSA...