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  1. Article

    Open Access

    Caffeic acid phenethyl ester decreases acute pneumonitis after irradiation in vitro and in vivo

    Lung cancer is relatively resistant to radiation treatment and radiation pneumonitis is a major obstacle to increasing the radiation dose. We previously showed that Caffeic acid phenethyl ester (CAPE) induces ...

    Miao-Fen Chen, Peter C Keng, Paul-Yang Lin, Cheng-Ta Yang, Shuen-Kuei Liao in BMC Cancer (2005)

  2. Article

    Open Access

    Serum diagnosis of diffuse large B-cell lymphomas and further identification of response to therapy using SELDI-TOF-MS and tree analysis patterning

    Currently, there are no satisfactory biomarkers available to screen for diffuse large B cell lymphoma (DLBCL) or to identify patients who do not benefit from standard anti-cancer therapies. In this study, we u...

    **ng Zhang, Bo Wang, **ao-shi Zhang, Zhi-ming Li, Zhong-zhen Guan in BMC Cancer (2007)

  3. Article

    Open Access

    Clinical and prognostic analysis of hepatitis B virus infection in diffuse large B-cell lymphoma

    Hepatitis B virus (HBV) infection in diffuse large B-cell lymphoma (DLBCL) patients is a common complication in China. However, the clinical relevance of HBV infection with respect to DLBCL disease stages and ...

    Feng Wang, Rui-hua Xu, Hui-yan Luo, Dong-shen Zhang, Wen-qi Jiang in BMC Cancer (2008)

  4. Article

    Open Access

    Improved therapeutic effectiveness by combining liposomal honokiol with cisplatin in lung cancer model

    Honokiol is a major bioactive compound extracted from Magnolia. The present study was designed to determine whether liposomal honokiol has the antitumor activity against human lung cancer as well as potentiate...

    Qi-qi Jiang, Lin-yu Fan, Guang-li Yang, Wen-Hao Guo, Wen-li Hou, Li-juan Chen in BMC Cancer (2008)

  5. Article

    Open Access

    Androgen deprivation modulates the inflammatory response induced by irradiation

    The aim of this study was to determine whether radiation (RT)-induced inflammatory responses and organ damage might be modulated by androgen deprivation therapies.

    Chun-Te Wu, Wen-Cheng Chen, Paul-Yang Lin, Shuen-Kuei Liao, Miao-Fen Chen in BMC Cancer (2009)

  6. Article

    Open Access

    Activation of P2X7-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice

    The study tested the hypothesis that apoptosis can prevent and control growth of neoplastic cells. Previous studies in-vitro have shown that the pro-apoptotic P2X7 receptor regulates growth of epithelial cells. T...

    Wen Fu, Tom McCormick, ** Qi, Li** Luo, Lingyin Zhou, **n Li in BMC Cancer (2009)

  7. Article

    Open Access

    Expression of ezrin is associated with invasion and dedifferentiation of hepatitis B related hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is the fifth most common malignancy in the world and constitutes the leading cause of cancer-related death among men, and second among women in Taiwan. Liver cirrhosis and HCC ar...

    Chun-Nan Yeh, See-Tong Pang, Tsung-Wen Chen, Ren-Ching Wu, Wen-Hui Weng in BMC Cancer (2009)

  8. Article

    Open Access

    Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR)

    Recent reports indicate the existence of breast cancer cells expressing very high levels of the Arylhydrocarbon receptor (AhR), a ubiquitous intracellular receptor best known for mediating toxic action of diox...

    Patrick S Wong, Wen Li, Christoph F Vogel, Fumio Matsumura in BMC Cancer (2009)

  9. Article

    Open Access

    Assessment of the effect of betaine on p16 and c-mycDNA methylation and mRNA expression in a chemical induced rat liver cancer model

    The development and progression of liver cancer may involve abnormal changes in DNA methylation, which lead to the activation of certain proto-oncogenes, such as c-myc, as well as the inactivation of certain tumo...

    Yan-** Du, Jun-sheng Peng, Ai Sun, Zhi-hong Tang, Wen-hua Ling in BMC Cancer (2009)

  10. Article

    Open Access

    Limitations in SELDI-TOF MS whole serum proteomic profiling with IMAC surface to specifically detect colorectal cancer

    Surface enhanced laser desorption and ionization time-of-flight mass spectrometry (SELDI-TOF-MS) analysis on serum samples was reported to be able to detect colorectal cancer (CRC) from normal or control patie...

    Qi Wang, **g Shen, Zhen-fu Li, Jian-zheng Jie, Wen-yue Wang, ** Wang in BMC Cancer (2009)

  11. Article

    Open Access

    Overexpression of human sperm protein 17 increases migration and decreases the chemosensitivity of human epithelial ovarian cancer cells

    Most deaths from ovarian cancer are due to metastases that are resistant to conventional therapies. But the factors that regulate the metastatic process and chemoresistance of ovarian cancer are poorly underst...

    Fang-qiu Li, Yan-ling Han, Qun Liu, Bo Wu, Wen-bin Huang, Su-yun Zeng in BMC Cancer (2009)

  12. Article

    Open Access

    The investigation of Mitogen-Activated Protein kinase Phosphatase-1 as a potential pharmacological target in non-small cell lung carcinomas, assisted by non-invasive molecular imaging

    Invasiveness and metastasis are the most common characteristics of non small cell lung cancer (NSCLC) and causes of tumour-related morbidity and mortality. Mitogen-activated protein kinases (MAPKs) signalling ...

    Cheng-Jeng Tai, Alexander TH Wu, Jeng-Feng Chiou, Hsun-** Jan, Hon-Jian Wei in BMC Cancer (2010)

  13. Article

    Open Access

    Long-term results of intensity-modulated radiotherapy concomitant with chemotherapy for hypopharyngeal carcinoma aimed at laryngeal preservation

    The objective of this retrospective study is to investigate laryngeal preservation and long-term treatment results in hypopharyngeal carcinoma treated with intensity-modulated radiotherapy (IMRT) combined with...

    Wen-Shan Liu, Chung-Han Hsin, Ying-Hsiang Chou, Jung-Tung Liu, Ming-Fang Wu in BMC Cancer (2010)

  14. Article

    Open Access

    Association between TGFBR1*6A and osteosarcoma: A Chinese case-control study

    TGFBR1*6A is a common hypomorphic variant of transforming growth factor β receptor 1 (TGFBR1). TGFBR1*6A is associated with an increased cancer risk, but the association of this polymorphism with osteosarcoma ...

    Yun-Sheng Hu, Yong Pan, Wen-Hai Li, Yong Zhang, Jun Li, Bao-An Ma in BMC Cancer (2010)

  15. Article

    Open Access

    Residual hepatocellular carcinoma after oxaliplatin treatment has increased metastatic potential in a nude mouse model and is attenuated by Songyou Yin

    The opposite effects of chemotherapy, which enhance the malignancy of treated cancers such as hepatocellular carcinoma (HCC), are not well understood. We investigated this phenomenon and corresponding mechanis...

    Wei **ong, Zheng-Gang Ren, Shuang-Jian Qiu, Hui-Chuan Sun, Lu Wang in BMC Cancer (2010)

  16. Article

    Open Access

    Incidence of chemotherapy-induced amenorrhea associated with epirubicin, docetaxel and navelbine in younger breast cancer patients

    The rates of chemotherapy-induced amenorrhea (CIA) associated with docetaxel-based regimens reported by previous studies are discordant. For navelbine-based chemotherapies, rates of CIA have seldom been reported.

    Wen-Bin Zhou, Hong Yin, **ao-An Liu, **ao-Ming Zha, Lin Chen, Jun-Cheng Dai in BMC Cancer (2010)

  17. Article

    Open Access

    Traditional Cantonese diet and nasopharyngeal carcinoma risk: a large-scale case-control study in Guangdong, China

    Nasopharyngeal carcinoma (NPC) is rare in most parts of the world but is a common malignancy in southern China, especially in Guangdong. Dietary habit is regarded as an important modifier of NPC risk in severa...

    Wei-Hua Jia, **ang-Yu Luo, Bing-Jian Feng, Hong-Lian Ruan, **-**n Bei in BMC Cancer (2010)

  18. Article

    Open Access

    Predictive factors of radiation-induced skin toxicity in breast cancer patients

    To assess the factors affecting the incidence of radiation-induced dermatitis in breast cancer patients treated with adjuvant 3 D conformal radiotherapy by the analysis of dosimetry and topical treatments.

    Miao-Fen Chen, Wen-Cheng Chen, Chia-Hsuan Lai, Chao-hsiung Hung, Kuo-Chi Liu in BMC Cancer (2010)

  19. Article

    Open Access

    Neck dissection and post-operative chemotherapy with dimethyl triazeno imidazole carboxamide and cisplatin protocol are useful for oral mucosal melanoma

    Oral mucosal melanoma (OMM) is a clinically rare disease with poor prognosis. Various treatment methods have been investigated with the aim of improving the prognosis. This study aimed to analyze the data of a...

    ** Yang, Guo-xin Ren, Chen-** Zhang, Guo-yu Zhou, Yong-jie Hu, Wen-jun Yang in BMC Cancer (2010)

  20. Article

    Open Access

    Meta-analysis of quantitative diffusion-weighted MR imaging in the differential diagnosis of breast lesions

    To determine, in a meta-analysis, the diagnostic performance of quantitative diffusion-weighted (DW) MR imaging in patients with breast lesions.

    **n Chen, Wen-ling Li, Yi-li Zhang, Qian Wu, You-min Guo, Zhi-lan Bai in BMC Cancer (2010)

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