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Article
Open AccessGenome wide identification of novel DNA methylation driven prognostic markers in colorectal cancer
Colorectal cancer (CRC) stands as a major contributor to cancer-related fatalities within China. There is an urgent need to identify accurate biomarkers for recurrence predicting in CRC. Reduced representation...
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Article
Open AccessBlood leukocytes as a non-invasive diagnostic tool for thyroid nodules: a prospective cohort study
Thyroid nodule (TN) patients in China are subject to overdiagnosis and overtreatment. The implementation of existing technologies such as thyroid ultrasonography has indeed contributed to the improved diagnost...
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Article
Open AccessIodine monitoring models contribute to avoid adverse birth outcomes related more than adequate iodine intake
Iodine plays an important role in pregnancy. How to maintain adequate iodine intake amongst pregnant women in each trimester of pregnancy to prevent adverse birth outcomes in central China is a challenge for c...
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Article
Mutational profiling of lung adenocarcinoma in China detected by next-generation sequencing
NSCLC is the most common type of lung cancers. The purpose of this study is to screen cancer-related mutations in early LUAD in China through NGS technology, determine their correlation with clinical character...
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Article
Open AccessAssociation between carotid intima media thickness and small dense low-density lipoprotein cholesterol in acute ischaemic stroke
Intima-media thickness (IMT) and small dense low-density lipoprotein cholesterol (sdLDL-C) have been reported to be related to atherosclerosis and stroke. This study is trying to explore the association betwee...
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Article
Open AccessRNA virus receptor Rig-I monitors gut microbiota and inhibits colitis-associated colorectal cancer
Retinoic acid-inducible gene-I (Rig-I) is an intracellular viral RNA receptor, which specifically recognizes double-stranded viral RNA initiating antiviral innate immunity. Increasing evidences showed that Rig...