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Open AccessPopulation differentiation and dynamics of five pioneer species of Gaultheria from the secondary forests in subtropical China
The influence of native secondary succession associated with anthropogenic disturbance on the biodiversity of the forests in subtropical China remains uncertain. In particular, the evolutionary response of sma...
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Article
Open AccessSingle-nucleotide variant calling in single-cell sequencing data with Monopogen
Single-cell omics technologies enable molecular characterization of diverse cell types and states, but how the resulting transcriptional and epigenetic profiles depend on the cell’s genetic background remains ...
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Article
Open AccessA small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease with a high mortality rate. Putative drug targets in IPF have failed to translate into effective therapies at the clinical level. ...
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Article
Open AccessA chromosome-level genome assembly for the Silkie chicken resolves complete sequences for key chicken metabolic, reproductive, and immunity genes
A set of high-quality pan-genomes would help identify important genes that are still hidden/incomplete in bird reference genomes. In an attempt to address these issues, we have assembled a de novo chromosome-l...
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Article
BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules
Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, powered congression of those chromosomes, their segregation in anaphase, and assembly of a spindle midzone at mitotic exit....
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Article
Expression of Wheat Gibberellins 2-oxidase Gene Induced Dwarf or Semi-dwarf Phenotype in Rice
Gibberellins (GAs) are a class of plant hormones that play important roles in diverse aspects during plant growth and development. A series of GA synthesis and metabolism genes have been reported or proved to ...
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Article
Optimization of drug combinations using Feedback System Control
Nowak-Sliwinska et al. describe a protocol for optimizing drug combinations using Feedback System Control (FSC). Drug combinations are tested in a cell-based assay in which results are entered into the FSC pipeli...
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Article
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale
A statistical approach to quantitatively derive single and double mutant fitness from colony-based growth assays is described. The resultant SGA score permits assessment of yeast fitness and genetic interactio...
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Abstracts of presentations on plant protection issues at the xth international congress of virology
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Abstracts of presentations on plant protection issues at the fifth international Mango Symposium Abstracts of presentations on plant protection issues at the Xth international congress of Virology