273 Result(s)
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Article
Ting-**ang Xu
Biomedicine
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Article
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection
Although maternal human immunodeficiency virus type 1 (HIV-1) transmission occurs during gestation, intrapartum and postpartum (by breast-feeding), 50–70% of all infected children seem to acquire HIV-1 shortly...
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Changes of ATP and ADP in Cultured Astrocytes Under and After in Vitro Ischemia
A very large body of evidence from in vivo studies has been accumulated on a link between the change of energy and cell survival/apoptosis. Using an in vitro ischemia model, we have previously shown that ische...
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Pharmacokinetic behaviors and oral bioavailability of oridonin in rat plasma
To study the intravenous and oral pharmacokinetic behavior of oridonin and its extent of absolute oral bioavailability in rats.
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Effect of Electroacupuncture on Neurotrophin Expression in Cat Spinal Cord after Partial Dorsal Rhizotomy
Neuroplasticity of the spinal cord following electroacupuncture (EA) has been demonstrated although little is known about the possible underlying mechanism. This study evaluated the effect of EA on expression ...
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Electro-acupuncture Reduces Neuronal Apoptosis Linked to Bax and Bcl-2 Expression in the Spinal Cords of Cats Subjected to Partial Dorsal Root Ganglionectomy
While electro-acupuncture (EA) has been well known to contribute towards neuroplasticity occurring in both the central and the peripheral nervous system after injury, the underlying mechanism remains largely u...
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Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21
Xuejun Zhang and colleagues report a genome-wide association and replication studies for psoriasis, conducted in Chinese populations. They confirm previous associations in MHC and IL12B to psoriasis susceptibilit...
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Electroacupuncture Induced Spinal Plasticity is Linked to Multiple Gene Expressions in Dorsal Root Deafferented Rats
The underlying mechanism for electroacupuncture (EA) associated functional improvement in patients suffering from spinal cord injury (SCI) is largely unknown. Collateral sprouting is one plausible factor, wher...
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Oxidative damage increased in presenilin1/presenilin2 conditional double knockout mice
This report aims to describe the oxidative damage profile in brain of presenilin1 and presenilin2 conditional double knockout mice (dKO) at both early and late age stages, and to discuss the correlation between o...
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Recombinant DNA Vaccine Against Inhibition of Neurite Outgrowth Promotes Functional Recovery Associated with Endogeous NGF Expression in Spinal Cord Hemisected Adult Rats
Axonal regeneration across the site of spinal cord lesion is often aborted in adult mammalian species. The use of DNA vaccine to nullify the inhibitory molecules has been shown to be effective in promoting axo...
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Erratum to: Recombinant DNA Vaccine Against Inhibition of Neurite Outgrowth Promotes Functional Recovery Associated with Endogeous NGF Expression in Spinal Cord Hemisected Adult Rats
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Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC
Youwen Zhou and Xue-Jun Zhang and colleagues report a genome-wide association study of generalized vitiligo, a common autoimmune disorder characterized by loss of melanocytes and depigmentation. The authors id...
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Cordycepin induces apoptosis by enhancing JNK and p38 kinase activity and increasing the protein expression of Bcl-2 pro-apoptotic molecules
To explore the molecular mechanism by which cordycepin inhibits cell proliferation and induces apoptosis of human colorectal cancer cells.
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Effects of Taurine on Glial Cells Apoptosis and Taurine Transporter Expression in Retina Under Diabetic Conditions
Taurine, a ß-aminosulfonic acid, has been reported to reduce the risk of a number of diseases, including cardiovascular disease, diabetes, and also perhaps to reduce neurodegeneration in the elderly. The transpor...
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Open AccessPrognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma
Oct4 and Sox2 are two major transcription factors related to the stem cell self-renewal and differentiation. The aim of this study was to examine the association between Oct4 and Sox2 expression levels with bo...
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Open AccessSeroprevalence of Toxoplasma gondii infection in dairy goats in Shaanxi Province, Northwestern China
Toxoplasma gondii is an important zoonotic pathogen causing significant human and animal health problems. Infection in dairy goats not only results in significant reproductive losses, but also represents an impor...
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Open AccessPerformance of a dipstick dye immunoassay for rapid screening of Schistosoma japonicum infection in areas of low endemicity
The dipstick dye immunoassay (DDIA), recently commercially available in the People's Republic of China (P.R. China), is a rapid and simple test to detect human antibodies against Schistosoma Japonicum. Its perfor...
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Open AccessCharacteristics and PD-1 expression of peripheral CD4+CD127loCD25hiFoxP3+ Treg cells in chronic HCV infected-patients
Both regulatory T cells (Tregs) and PD-1/PD-L1 pathway were critically involved in HCV viral persistence. However, the association between them was not well investigated. Herein, we aimed to investigate the di...
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Open AccessNeurological abnormalities and neurocognitive functions in healthy elder people: A structural equation modeling analysis
Neurological abnormalities have been reported in normal aging population. However, most of them were limited to extrapyramidal signs and soft signs such as motor coordination and sensory integration have recei...
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Distribution of TRPC6 in the Cerebrospinal Fluid-Contacting Nucleus of Rat Brain Parenchyma and its Expression in Morphine Dependence and Withdrawal
To investigate the role of cerebrospinal fluid contacting nucleus (CSF-CN) and the changes of TRPC6 expression in morphine dependence and withdrawal. Male Sprague–Dawley rats (250 ± 50 g) were randomly divided...
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Opioids and HIV/HCV Infection
Since human immunodeficiency virus (HIV) and hepatitis C virus (HCV) share the same modes of transmission and common risk factors for infection, co-infections with HIV and HCV are frequently found in injection...
