36 Result(s)
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Ting Ting Liu
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Open AccessRadiomics models of contrast-enhanced computed tomography for predicting the activity and prognosis of acute pancreatitis
The modified pancreatitis activity scoring system (mPASS) was proposed to assess the activity of acute pancreatitis (AP) while it doesn’t include indicators that directly reflect pathophysiology processes and ...
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Open AccessP2X7 receptor: a potential target for treating comorbid anxiety and depression
In clinical practice, depression and anxiety frequently coexist, and they are both comorbid with somatic diseases. The P2X7R is an adenosine 5’-triphosphate (ATP)-gated non-selective cation channel that is wid...
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Open AccessIn Situ Atomic Reconstruction Engineering Modulating Graphene-Like MXene-Based Multifunctional Electromagnetic Devices Covering Multi-Spectrum
MXene/TiO2 hybrids are prepared by a simple calcination treatment, and their electromagnetic response is customized by in situ atomic reconstruction engineering.
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Open AccessAccidental ingestion of multiple magnetic beads by children and their impact on the gastrointestinal tract: a single-center study
In this study, we aimed to enhance the treatment protocols and help understand the harm caused by the accidental ingestion of magnetic beads by children.
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Open AccessC–C chemokine receptor 5 is essential for conventional NK cell trafficking and liver injury in a murine hepatitis virus-induced fulminant hepatic failure model
Previous studies have demonstrated that natural killer (NK) cells migrated into the liver from peripheral organs and exerted cytotoxic effects on hepatocytes in virus-induced liver failure.
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Open AccessThe prognostic significance of histologic variant on survival outcomes in patients with metastatic urothelial carcinoma receiving immune checkpoint inhibitor therapy
While the treatment guidelines have been established for pure urothelial carcinoma (pUC), patients with variant type urothelial carcinoma (vUC) face limited effective treatment options. The effectiveness of im...
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Open AccessAbnormal adenosine metabolism of neutrophils inhibits airway inflammation and remodeling in asthma model induced by Aspergillus fumigatus
Neutrophils consume a large amount of energy when performing their functions. Compared with other white blood cells, neutrophils contain few mitochondria and mainly rely on glycolysis and gluconeogenesis to pr...
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Open AccessATG4B and pS383/392-ATG4B serve as potential biomarkers and therapeutic targets of colorectal cancer
Autophagy related protease 4B (ATG4B) is a protease required for autophagy processing, which is strongly implicated in cancer progression. Phosphorylation of ATG4B is crucial for activation of its protease ac...
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Open AccessP2Y12 receptor gene polymorphisms are associated with epilepsy
The basic research indicated that microglial P2Y12 receptors (P2Y12Rs) are involved in the pathophysiology of epilepsy through regulated microglial-neuronal interactions, aberrant neurogenesis, or immature neuron...
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Open AccessThe partial waves of \(B^{*}_{2}(5747)\) and their contributions in strong decays
The relativistic Bethe–Salpeter method is adopted to study the OZI-allowed strong decays of the \(2^+\) ...
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Open AccessJunctional adhesion molecule-like protein promotes tumor progression via the Wnt/β-catenin signaling pathway in lung adenocarcinoma
Lung adenocarcinoma (LUAD) is a heavy social burden worldwide. Because the mechanisms involved in LUAD remain unclear, the prognosis of LUAD remains poor. Consequently, it is urgent to investigate the potentia...
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Open AccessDevelopment of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1
Immune checkpoint inhibition is an important strategy in cancer therapy. Blockade of CTLA-4 and PD-1/PD-L1 is well developed in clinical practice. In the last few years, LAG-3 has received much interest as an ...
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Open AccessIdentification and validation of a novel glycolysis-related gene signature for predicting the prognosis in ovarian cancer
Ovarian cancer (OC) is the most lethal gynaecological tumor. Changes in glycolysis have been proven to play an important role in OC progression. We aimed to identify a novel glycolysis-related gene signature t...
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Transient printing characteristics with wavy build profiles for laser additive manufacturing of small size structures
Laser directed energy deposition (DED) is a multi-physics process that accompanies mass flow, energy transfer, and complex phase transitions. The printing characteristics of small size parts are significantly ...
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Open AccessTNF-α acutely enhances acid-sensing ion channel currents in rat dorsal root ganglion neurons via a p38 MAPK pathway
Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine involved in pain processing and hypersensitivity. It regulates not only the expression of a variety of inflammatory mediators but also the functio...
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Open AccessCorrection: Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity
A Correction to this paper has been published: https://doi.org/10.1038/s41392-021-00533-3
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Open AccessSynthesis and antibacterial activity of novel myricetin derivatives containing sulfonylpiperazine
Myricetin derivatives containing sulfonylpiperazine were synthesized and their structures were confirmed by NMR and HRMS. The antibacterial activity results indicated that some compounds showed good antibacter...
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Open AccessSmall molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity
Mitochondrial fusion/fission dynamics plays a fundamental role in neuroprotection; however, there is still a severe lack of therapeutic targets for this biological process. Here, we found that the naturally de...
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Open AccessEpidemiological characteristics of spinal cord injury in Northwest China: a single hospital-based study
While the cities in China in which spinal cord injury (SCI) studies have been conducted previously are at the forefront of medical care, northwest China is relatively underdeveloped economically, and the epide...
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Open AccessGrading of Glioma: combined diagnostic value of amide proton transfer weighted, arterial spin labeling and diffusion weighted magnetic resonance imaging
To investigate the ability of amide proton transfer (APT) weighted magnetic resonance imaging (MRI), arterial spin labeling (ASL), diffusion weighted imaging (DWI) and the combination for differentiating high-...
