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Article

Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1

Osteosarcoma (OS) is the most frequent cancer derived from bone, and the prognosis of OS is poor. Metabolic alterations have been previously reported to contribute to the development of OS, and arsenic compoun...

Yixin Liu, Wenyan She, Yi Li, Miao Wang, Yin Liu… in Journal of Translational Medicine (2023)