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Open AccessCurcumin induces apoptosis in gallbladder carcinoma cell line GBC-SD cells
Gallbladder carcinoma is a malignant tumor with a very low 5-year survival rate because of the difficulty with its early diagnosis and the very poor prognosis of the advanced cancer state. The aims of this stu...
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Article
Open AccessThe complete mitochondrial genome of the scab mite Psoroptes cuniculi (Arthropoda: Arachnida) provides insights into Acari phylogeny
Limited available sequence information has greatly impeded population genetics, phylogenetics and systematics studies in the subclass Acari (mites and ticks). Mitochondrial (mt) DNA is well known to provide ge...
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Article
Bufalin induces cell cycle arrest and apoptosis in gallbladder carcinoma cells
Bufalin, a major digoxin-like immunoreactive component of the Chinese medicine Chan Su, has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro. However, no...
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Article
Synthesis of homogeneous one-dimensional Ni x Cd1−x S nanorods with enhanced visible-light response by ethanediamine-assisted decomposition of complex precursors
A route to fabricate the homogeneous one-dimensional (1D) Ni x Cd1−x S nanorods (NRs) photocatalysts is designed with ethanediamine-assisted decomposition of Ni ...
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Article
One-pot hydrothermal route to synthesize the ZnIn2S4/g-C3N4 composites with enhanced photocatalytic activity
Heterogeneous ZnIn2S4/g-C3N4 hybrid composites, as highly efficient visible-light-driven photocatalysts, were designed and fabricated by a simple one-step hydrothermal route for the first time, wherein the cubic ...
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Article
Homology modeling, docking, and molecular dynamics simulation of the receptor GALR2 and its interactions with galanin and a positive allosteric modulator
Galanin receptor type 2 (GALR2) is a class A G-protein-coupled receptor (GPCR), and it has been reported that orthosteric ligands and positive allosteric modulators (PAMs) of GALR2 could potentially be used to...
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Article
Calcium-dependent protein kinase (CDPK) and CDPK-related kinase (CRK) gene families in tomato: genome-wide identification and functional analyses in disease resistance
Calcium-dependent protein kinases (CDPKs) and CDPK-related kinases (CRKs) play multiple roles in plant. Nevertheless, genome-wide identification of these two families is limited to several plant species, and r...
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Article
Open AccessTripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer
TRIM62 (tripartite motif containing 62) has been found to act as a tumor suppressor of several cancers. However, its precise biological role and related mechanism remain unknown in cervical cancer (CC).
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Article
FABP5 correlates with poor prognosis and promotes tumor cell growth and metastasis in cervical cancer
Fatty acid-binding protein 5 (FABP5) was found in our previous study to be a potential biomarker for lymph node metastasis of cervical cancer. However, the roles of FABP5 in cervical cancer remain unclear. In ...
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Article
Influence of pulse magneto-oscillation on the efficiency of grain refiner
Solidification experiments were carried out in Al-Cu (w(Cu) = 5%) alloy to investigate the influence of pulse magneto-oscillation (PMO) on the efficiency of the Al3Ti1B refining agent at high superheat. The exper...
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Article
BTB domain-containing 7 predicts low recurrence and suppresses tumor progression by deactivating Notch1 signaling in breast cancer
BTB domain-containing 7 (BTBD7) has been found to regulate epithelial tissue remodeling and branched organ formation and has been reported to modulate the biological behavior of several cancers. However, its r...
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Article
Open AccessDevelopment and validation of a survival nomogram for patients with Siewert type II/III adenocarcinoma of the esophagogastric junction based on real-world data
The clinical staging systems for adenocarcinoma of the esophagogastric junction (AEG) are controversial. We aimed to propose a prognostic nomogram based on real-world data for predicting survival of Siewert ty...
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Article
Design for Ti-Al-V-Mo-Nb alloys for laser additive manufacturing based on a cluster model and on their microstructure and properties
In this study, α+β Ti-Al-V-Mo-Nb alloys with the addition of multiple elements that are suitable for laser additive manufacturing (LAM) were designed according to a Ti-6Al-4V cluster formula. This formula can ...
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Article
Microstructure and mechanical properties of laser additive manufactured novel titanium alloy after heat treatment
A novel α+β titanium alloy with multi-alloying addition was designed based on the cluster formula 12[Al-Ti12](AlTi2)+5[Al-Ti14](AlV12Mo06Nb02) which was derived from Ti-6Al-4V. The nominal composition of this nov...
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Article
Open AccessUltrafast modulation of valley dynamics in multiple WS2 − Ag gratings strong coupling system
Strong light-matter interactions in two-dimensional transition metal dichalcogenides (TMDCs) with robust spin-valley degrees of freedom open up the prospect of valleytronic devices. A thorough understanding on...
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Article
Effect of processing parameters on formability, microstructure, and micro-hardness of a novel laser additive manufactured Ti-6.38Al-3.87V-2.43Mo alloy
A novel Ti-6.38Al-3.87V-2.43Mo alloy was designed with a cluster formula of 12[Al-Ti12] (V0.75Mo0.25Ti2)+4[Al-Ti12](Al3) by replacing Ti with Mo/V on the basis of the Ti-Al congruent alloy. The effects of laser p...
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Article
CPEB3 suppresses gastric cancer progression by inhibiting ADAR1-mediated RNA editing via localizing ADAR1 mRNA to P bodies
Deciphering the crosstalk between RNA-binding proteins and corresponding RNAs will provide a better understanding of gastric cancer (GC) progression. The comprehensive bioinformatics study identified cytoplasm...
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Article
Composition formula of Al-TMs high-entropy alloys derived by cluster-plus-glue-atoms model and its experimental verification
High-entropy alloys (HEAs) are based on solid solutions which characterized by chemical short-range ordering (CSRO), but there is no accurate structural tool to address CSRO characteristic, which obstacles pre...
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Article
Effect of hot isostatic pressing processing parameters on microstructure and properties of Ti60 high temperature titanium alloy
Hot isostatic pressing parameters are critical to Ti60 high temperature titanium alloy castings which have wide application perspective in aerospace. In order to obtain optimal processing parameters, the effec...
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Article
High-strength Ti-Al-V-Zr cast alloys designed using α and β cluster formulas
Ti-Al-V-Zr quaternary titanium alloys were designed following α-{[Al-Ti12](AlTi2)}17−n+β-{[Al-Ti12Zr2](V3)}n, where n=1–7 (the number of β units), on the basis of the dual-cluster formula of popular Ti-6Al-4V all...