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  1. No Access

    Article

    Possible influence of the insertion/deletion polymorphism in the angiotensin I-converting enzyme gene on theraputic outcome in affective disorders

    T C Baghai, C Schüle, P Zwanzger, C Minov, M J Schwarz, S de Jonge… in Molecular Psychiatry (2001)

  2. No Access

    Article

    Combined action of the ACE D- and the G-protein β3 T-allele in major depression: a possible link to cardiovascular disease?

    Although it is well established that depression is a major risk factor for the development of coronary artery disease and that cerebrovascular disease can be a major contributing factor for the development of ...

    B Bondy, T C Baghai, P Zill, R Bottlender, M Jaeger, C Minov… in Molecular Psychiatry (2002)

  3. Article

    Effects of Alprazolam on Cholecystokinin-Tetrapeptide-Induced Panic and Hypothalamic–Pituitary–Adrenal-Axis Activity: A Placebo-Controlled Study

    Cholecystokinin-tetrapeptide (CCK-4) induces panic attacks both in patients with panic disorder (PD) and healthy volunteers. It has been shown that panic elicited by CCK-4 is improved after treatment with anti...

    P Zwanzger, D Eser, S Aicher, C Schüle, T C Baghai, F Padberg… in Neuropsychopharmacology (2003)

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    Article

    SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression

    Tryptophan hydroxylase (TPH), being the rate-limiting enzyme in the biosynthesis of serotonin plays a major role as candidate gene in several psychiatric disorders. Recently, a second TPH isoform (TPH2) was id...

    P Zill, T C Baghai, P Zwanzger, C Schüle, D Eser, R Rupprecht… in Molecular Psychiatry (2004)

  5. No Access

    Article

    Influence of mirtazapine on plasma concentrations of neuroactive steroids in major depression and on 3α-hydroxysteroid dehydrogenase activity

    Concentrations of 3α-reduced neuroactive steroids are altered in depression and normalize after antidepressant pharmacotherapy with selective serotonin re-uptake inhibitors (SSRIs). We investigated the impact of ...

    C Schüle, E Romeo, D P Uzunov, D Eser, F di Michele, T C Baghai… in Molecular Psychiatry (2006)

  6. No Access

    Article

    Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism

    Angiotensin-converting enzyme (ACE) is assumed to influence the activity of the hypothalamic-pituitary-adrenocortical (HPA) system, which shows hyperactivity in the majority of patients with major depression. ...

    T C Baghai, E B Binder, C Schule, D Salyakina, D Eser, S Lucae… in Molecular Psychiatry (2006)